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The von Willebrand Disease Prophylaxis Network (vWD PN): Exploring a treatment concept.

Berntorp, Erik LU and Abshire, Thomas (2006) In Thrombosis Research 18. p.19-22
Abstract
The von Willebrand Disease Prophylactic Network (vWD PN) has been initiated to study the natural history of vWD bleeding, and to prospectively study the role of von Willebrand Factor (vWF) concentrate prophylaxis in vWD. Patients with all types of vWD in need of treatment with vWF concentrate will be enrolled into the study. Quality of life will be measured and safety and efficacy will be monitored at pre-determined intervals. Between February 2005 and July 18, 2005, 62 investigators from Europe and North America were participating in the vWD PN, and 61 have submitted census data. A total 5343 patients have been identified for enrolment, and of these, 991 patients were treated with plasma-derived products in the preceding 12 months, and 99... (More)
The von Willebrand Disease Prophylactic Network (vWD PN) has been initiated to study the natural history of vWD bleeding, and to prospectively study the role of von Willebrand Factor (vWF) concentrate prophylaxis in vWD. Patients with all types of vWD in need of treatment with vWF concentrate will be enrolled into the study. Quality of life will be measured and safety and efficacy will be monitored at pre-determined intervals. Between February 2005 and July 18, 2005, 62 investigators from Europe and North America were participating in the vWD PN, and 61 have submitted census data. A total 5343 patients have been identified for enrolment, and of these, 991 patients were treated with plasma-derived products in the preceding 12 months, and 99 patients have received prophylaxis, predominantly for joint-related bleeds. The vWD PN aims to further elucidate the role of vWF concentrate prophylaxis in vWD and to identify patients most Likely to benefit from prophylaxis. (Less)
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type
Contribution to journal
publication status
published
subject
keywords
von Willebrand disease, Willebrand factor, prophylaxis, haemorrhage, von, factor VIII
in
Thrombosis Research
volume
18
pages
19 - 22
publisher
Elsevier Ltd
external identifiers
  • wos:000238200400005
  • scopus:33646056438
ISSN
1879-2472
DOI
10.1016/j.thromres.2006.01.016
language
English
LU publication?
yes
id
aa4e2b94-f71f-44ee-9603-e9d8dd7b9937 (old id 154538)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16545435&dopt=Abstract
date added to LUP
2016-04-01 12:12:50
date last changed
2020-01-12 09:25:24
@article{aa4e2b94-f71f-44ee-9603-e9d8dd7b9937,
  abstract     = {The von Willebrand Disease Prophylactic Network (vWD PN) has been initiated to study the natural history of vWD bleeding, and to prospectively study the role of von Willebrand Factor (vWF) concentrate prophylaxis in vWD. Patients with all types of vWD in need of treatment with vWF concentrate will be enrolled into the study. Quality of life will be measured and safety and efficacy will be monitored at pre-determined intervals. Between February 2005 and July 18, 2005, 62 investigators from Europe and North America were participating in the vWD PN, and 61 have submitted census data. A total 5343 patients have been identified for enrolment, and of these, 991 patients were treated with plasma-derived products in the preceding 12 months, and 99 patients have received prophylaxis, predominantly for joint-related bleeds. The vWD PN aims to further elucidate the role of vWF concentrate prophylaxis in vWD and to identify patients most Likely to benefit from prophylaxis.},
  author       = {Berntorp, Erik and Abshire, Thomas},
  issn         = {1879-2472},
  language     = {eng},
  pages        = {19--22},
  publisher    = {Elsevier Ltd},
  series       = {Thrombosis Research},
  title        = {The von Willebrand Disease Prophylaxis Network (vWD PN): Exploring a treatment concept.},
  url          = {http://dx.doi.org/10.1016/j.thromres.2006.01.016},
  doi          = {10.1016/j.thromres.2006.01.016},
  volume       = {18},
  year         = {2006},
}