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Non-contact acoustic capture of platelet-derived microparticles from small plasma volumes

Evander, Mikael LU ; Gidlöf, Olof LU ; Olde, Björn LU ; Erlinge, David LU and Laurell, Thomas LU (2015) 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences p.469-471
Abstract

This paper presents the characterization and optimization of acoustic capture of platelet-derived microparticles (PMPs) from human plasma. The technique is compared to a standard preparation protocol using differential centrifugation on biobank samples from patients with ST-elevation myocardial infarction (STEMI). The main advantages of this new method are the capability of rapidly capturing microvesicles from small sample volumes and the potential to extract intact vesicles for downstream processing or handling.

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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Acoustic trapping, Acoustofluidics, Enrichment, Extracellular vesicles, Microparticles
in
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
pages
3 pages
publisher
Chemical and Biological Microsystems Society
conference name
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
external identifiers
  • scopus:84983335553
ISBN
9780979806483
language
English
LU publication?
yes
id
b8b11cc2-7fe3-47a8-9de3-7bd01659ce92
date added to LUP
2016-12-21 09:48:29
date last changed
2017-01-01 08:44:07
@inproceedings{b8b11cc2-7fe3-47a8-9de3-7bd01659ce92,
  abstract     = {<p>This paper presents the characterization and optimization of acoustic capture of platelet-derived microparticles (PMPs) from human plasma. The technique is compared to a standard preparation protocol using differential centrifugation on biobank samples from patients with ST-elevation myocardial infarction (STEMI). The main advantages of this new method are the capability of rapidly capturing microvesicles from small sample volumes and the potential to extract intact vesicles for downstream processing or handling.</p>},
  author       = {Evander, Mikael and Gidlöf, Olof and Olde, Björn and Erlinge, David and Laurell, Thomas},
  booktitle    = {MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences},
  isbn         = {9780979806483},
  keyword      = {Acoustic trapping,Acoustofluidics,Enrichment,Extracellular vesicles,Microparticles},
  language     = {eng},
  pages        = {469--471},
  publisher    = {Chemical and Biological Microsystems Society},
  title        = {Non-contact acoustic capture of platelet-derived microparticles from small plasma volumes},
  year         = {2015},
}