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Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?

Barker, Roger A LU ; Björklund, Anders LU orcid ; Frucht, Steven J and Svendsen, Clive N (2021) In Journal of Parkinson's Disease 11(3). p.909-917
Abstract

The use of stem cell derived dopamine neurons for treating patients with Parkinson's disease has now evolved to the first in human clinical trials. In this debate, we argue that assuming these trials give positive outcomes that this therapy will supercede DBS as the neurosurgical treatment of choice for PD patients in the future given it is a one-off therapy that repairs a critical pathway in the parkinsonian brain.

Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Parkinson's Disease
volume
11
issue
3
pages
9 pages
publisher
IOS Press
external identifiers
  • scopus:85112139016
  • pmid:34334425
ISSN
1877-718X
DOI
10.3233/JPD-219008
language
English
LU publication?
yes
id
bbdefa07-82ba-480c-b78c-119e769e9aa0
date added to LUP
2021-08-03 16:25:36
date last changed
2024-04-06 06:27:18
@article{bbdefa07-82ba-480c-b78c-119e769e9aa0,
  abstract     = {{<p>The use of stem cell derived dopamine neurons for treating patients with Parkinson's disease has now evolved to the first in human clinical trials. In this debate, we argue that assuming these trials give positive outcomes that this therapy will supercede DBS as the neurosurgical treatment of choice for PD patients in the future given it is a one-off therapy that repairs a critical pathway in the parkinsonian brain.</p>}},
  author       = {{Barker, Roger A and Björklund, Anders and Frucht, Steven J and Svendsen, Clive N}},
  issn         = {{1877-718X}},
  language     = {{eng}},
  month        = {{07}},
  number       = {{3}},
  pages        = {{909--917}},
  publisher    = {{IOS Press}},
  series       = {{Journal of Parkinson's Disease}},
  title        = {{Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?}},
  url          = {{http://dx.doi.org/10.3233/JPD-219008}},
  doi          = {{10.3233/JPD-219008}},
  volume       = {{11}},
  year         = {{2021}},
}