Recurrent and other new foot ulcers after healed plantar forefoot diabetic ulcer
(2017) In Wound Repair and Regeneration 25(2). p.309-315- Abstract
Diabetic foot ulcer is a serious complication in patients with diabetes. In most outcome studies of this condition, there is a combination of various types of ulcer and ulcer locations. Plantar ulcers are usually localized to the forefoot, and constitute a quarter of all diabetic foot ulcers. There are a limited number of studies regarding development of new ulcers following healing of a plantar forefoot ulcer, and there are no uniform definitions of recurrent and other new ulcers. The aim of this study was to evaluate the outcome of a large cohort of consecutively treated patients with diabetes mellitus and a healed planter forefoot ulcer (n = 617) with regard to development, characteristics, and outcome of recurrent and other new... (More)
Diabetic foot ulcer is a serious complication in patients with diabetes. In most outcome studies of this condition, there is a combination of various types of ulcer and ulcer locations. Plantar ulcers are usually localized to the forefoot, and constitute a quarter of all diabetic foot ulcers. There are a limited number of studies regarding development of new ulcers following healing of a plantar forefoot ulcer, and there are no uniform definitions of recurrent and other new ulcers. The aim of this study was to evaluate the outcome of a large cohort of consecutively treated patients with diabetes mellitus and a healed planter forefoot ulcer (n = 617) with regard to development, characteristics, and outcome of recurrent and other new ulcers. Patients were followed consecutively and prospectively with a 2-year follow-up, according to a preset protocol. Out of 617 patients, 250 (41%) did not develop any new ulcer, 262 (42%) developed a new ulcer, 87 (14%) died and 18 (3%) were lost at 2 years following healing of a plantar forefoot ulcer. Thirty-four percent developed other new ulcers (112 on the same foot and 99 on the contralateral foot), whereas 51 patients (8%) developed a recurrent ulcer (at the same site and foot). Of the patients who died within 2 years, 30 patients had developed other new ulcers. The risk of a recurrent ulcer in patients with diabetes and a healed plantar forefoot ulcer was only 8% within 2 years, whereas other new ulcers, on the same foot or on the contralateral foot, was seen in 4 out of 10 patients indicating the need for further preventive measures and surveillance in these patients. We suggest a concise definition for new ulcer to be used in future research.
(Less)
- author
- Örneholm, Hedvig LU ; Apelqvist, Jan LU ; Larsson, Jan and Eneroth, Magnus LU
- organization
- publishing date
- 2017-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Wound Repair and Regeneration
- volume
- 25
- issue
- 2
- pages
- 7 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:28370839
- wos:000403476200014
- scopus:85020805442
- ISSN
- 1067-1927
- DOI
- 10.1111/wrr.12522
- language
- English
- LU publication?
- yes
- id
- bf4bd8e1-fb48-452e-a683-f267f87a8e29
- date added to LUP
- 2017-08-21 11:30:48
- date last changed
- 2025-01-07 18:58:50
@article{bf4bd8e1-fb48-452e-a683-f267f87a8e29,
abstract = {{<p>Diabetic foot ulcer is a serious complication in patients with diabetes. In most outcome studies of this condition, there is a combination of various types of ulcer and ulcer locations. Plantar ulcers are usually localized to the forefoot, and constitute a quarter of all diabetic foot ulcers. There are a limited number of studies regarding development of new ulcers following healing of a plantar forefoot ulcer, and there are no uniform definitions of recurrent and other new ulcers. The aim of this study was to evaluate the outcome of a large cohort of consecutively treated patients with diabetes mellitus and a healed planter forefoot ulcer (n = 617) with regard to development, characteristics, and outcome of recurrent and other new ulcers. Patients were followed consecutively and prospectively with a 2-year follow-up, according to a preset protocol. Out of 617 patients, 250 (41%) did not develop any new ulcer, 262 (42%) developed a new ulcer, 87 (14%) died and 18 (3%) were lost at 2 years following healing of a plantar forefoot ulcer. Thirty-four percent developed other new ulcers (112 on the same foot and 99 on the contralateral foot), whereas 51 patients (8%) developed a recurrent ulcer (at the same site and foot). Of the patients who died within 2 years, 30 patients had developed other new ulcers. The risk of a recurrent ulcer in patients with diabetes and a healed plantar forefoot ulcer was only 8% within 2 years, whereas other new ulcers, on the same foot or on the contralateral foot, was seen in 4 out of 10 patients indicating the need for further preventive measures and surveillance in these patients. We suggest a concise definition for new ulcer to be used in future research.</p>}},
author = {{Örneholm, Hedvig and Apelqvist, Jan and Larsson, Jan and Eneroth, Magnus}},
issn = {{1067-1927}},
language = {{eng}},
month = {{03}},
number = {{2}},
pages = {{309--315}},
publisher = {{Wiley-Blackwell}},
series = {{Wound Repair and Regeneration}},
title = {{Recurrent and other new foot ulcers after healed plantar forefoot diabetic ulcer}},
url = {{http://dx.doi.org/10.1111/wrr.12522}},
doi = {{10.1111/wrr.12522}},
volume = {{25}},
year = {{2017}},
}