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Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images

Erlöv, Tobias LU ; Sheikh, Rafi LU orcid ; Dahlstrand, Ulf LU ; Albinsson, John LU ; Malmsjö, Malin LU and Cinthio, Magnus LU (2021) In Biomedical Optics Express 12(6). p.3312-3322
Abstract (Swedish)
In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of... (More)
In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Image quality, In vivo imaging, Optical flow, Photoacoustic imaging, Spatial resolution, Spectral imaging
in
Biomedical Optics Express
volume
12
issue
6
pages
11 pages
publisher
Optical Society of America
external identifiers
  • scopus:85105985644
  • pmid:34221662
ISSN
2156-7085
DOI
10.1364/BOE.421644
language
Swedish
LU publication?
yes
id
c0723a59-9c1e-4be7-82ee-300af7b4dec4
alternative location
http://www.osapublishing.org/boe/abstract.cfm?URI=boe-12-6-3312
date added to LUP
2021-05-17 14:57:05
date last changed
2022-04-27 01:58:01
@article{c0723a59-9c1e-4be7-82ee-300af7b4dec4,
  abstract     = {{In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans.}},
  author       = {{Erlöv, Tobias and Sheikh, Rafi and Dahlstrand, Ulf and Albinsson, John and Malmsjö, Malin and Cinthio, Magnus}},
  issn         = {{2156-7085}},
  keywords     = {{Image quality; In vivo imaging; Optical flow; Photoacoustic imaging; Spatial resolution; Spectral imaging}},
  language     = {{swe}},
  month        = {{05}},
  number       = {{6}},
  pages        = {{3312--3322}},
  publisher    = {{Optical Society of America}},
  series       = {{Biomedical Optics Express}},
  title        = {{Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images}},
  url          = {{http://dx.doi.org/10.1364/BOE.421644}},
  doi          = {{10.1364/BOE.421644}},
  volume       = {{12}},
  year         = {{2021}},
}