Advanced

Frailty and prediction of recurrent falls over 10 years in a community cohort of 75-year-old women

Bartosch, Patrik S. LU ; Kristensson, Jimmie LU ; McGuigan, Fiona E. LU and Akesson, Kristina E. LU (2020) In Aging clinical and experimental research 32(11). p.2241-2250
Abstract

Background: Frailty captures the age-related declines in health leading to increased vulnerability, including falls which are commonplace in older women. The relationship between frailty and falls is complex, with one leading to the other in a vicious cycle. Aims: This study addresses the gap in understanding how patterns of frailty and falls propensity interact, particularly in those who have not yet entered the falls-frailty cycle. Methods: The Osteoporosis Risk Assessment cohort consists of 1044 community-dwelling women aged 75, with 10 years of follow-up. Investigations were performed and a frailty index constructed at baseline, 5 and 10 years. Falls were self-reported for each previous 12 months. Analysis was two-directional,... (More)

Background: Frailty captures the age-related declines in health leading to increased vulnerability, including falls which are commonplace in older women. The relationship between frailty and falls is complex, with one leading to the other in a vicious cycle. Aims: This study addresses the gap in understanding how patterns of frailty and falls propensity interact, particularly in those who have not yet entered the falls-frailty cycle. Methods: The Osteoporosis Risk Assessment cohort consists of 1044 community-dwelling women aged 75, with 10 years of follow-up. Investigations were performed and a frailty index constructed at baseline, 5 and 10 years. Falls were self-reported for each previous 12 months. Analysis was two-directional, firstly based on frailty status and second, based on falls status. Recurrent falls was the primary outcome. Results: Baseline frailty was a significant predictor of recurrent falls after 5 and 10 years [(OR 2.55 (1.62–3.99); 3.04 (1.63–5.67)]. Among women who had no history of falls at age 75, frailty was a stronger predictor of falls at 5 years [OR 3.06 (1.59–5.89)] than among women who had previously fallen. Discussion: Frailty is significantly associated with recurrent falls and most pronounced in those who are frail but have not yet fallen. Conclusions: This suggests that frailty should be an integral part of falls-risk assessment to improve identification of those at risk of becoming fallers.

(Less)
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Community-dwelling, Falls, Frailty, Women
in
Aging clinical and experimental research
volume
32
issue
11
pages
10 pages
publisher
Kurtis
external identifiers
  • scopus:85078614962
  • pmid:31939201
ISSN
1594-0667
DOI
10.1007/s40520-019-01467-1
language
English
LU publication?
yes
id
c33c84e3-3e20-4159-87f2-802026e20726
date added to LUP
2020-02-13 14:29:42
date last changed
2021-04-27 04:22:42
@article{c33c84e3-3e20-4159-87f2-802026e20726,
  abstract     = {<p>Background: Frailty captures the age-related declines in health leading to increased vulnerability, including falls which are commonplace in older women. The relationship between frailty and falls is complex, with one leading to the other in a vicious cycle. Aims: This study addresses the gap in understanding how patterns of frailty and falls propensity interact, particularly in those who have not yet entered the falls-frailty cycle. Methods: The Osteoporosis Risk Assessment cohort consists of 1044 community-dwelling women aged 75, with 10 years of follow-up. Investigations were performed and a frailty index constructed at baseline, 5 and 10 years. Falls were self-reported for each previous 12 months. Analysis was two-directional, firstly based on frailty status and second, based on falls status. Recurrent falls was the primary outcome. Results: Baseline frailty was a significant predictor of recurrent falls after 5 and 10 years [(OR 2.55 (1.62–3.99); 3.04 (1.63–5.67)]. Among women who had no history of falls at age 75, frailty was a stronger predictor of falls at 5 years [OR 3.06 (1.59–5.89)] than among women who had previously fallen. Discussion: Frailty is significantly associated with recurrent falls and most pronounced in those who are frail but have not yet fallen. Conclusions: This suggests that frailty should be an integral part of falls-risk assessment to improve identification of those at risk of becoming fallers.</p>},
  author       = {Bartosch, Patrik S. and Kristensson, Jimmie and McGuigan, Fiona E. and Akesson, Kristina E.},
  issn         = {1594-0667},
  language     = {eng},
  number       = {11},
  pages        = {2241--2250},
  publisher    = {Kurtis},
  series       = {Aging clinical and experimental research},
  title        = {Frailty and prediction of recurrent falls over 10 years in a community cohort of 75-year-old women},
  url          = {http://dx.doi.org/10.1007/s40520-019-01467-1},
  doi          = {10.1007/s40520-019-01467-1},
  volume       = {32},
  year         = {2020},
}