Umbilical cord clamping in the early phases of the COVID-19 era - A systematic review and meta-analysis of reported practice and recommendations in guidelines
Berg, Johan LU
; Thies-Lagergren, Li
LU
; Svedenkrans, Jenny
LU
; Samkutty, Jeremiah
; Larsson, Sara Marie
LU
; Mercer, Judith S
; Rabe, Heike
; Andersson, Ola
LU
and Zaigham, Mehreen
LU
(2023)
In International Journal of Infectious Diseases
137.
p.63-70
- Abstract
OBJECTIVES: In the beginning of the COVID-19 pandemic, delayed umbilical cord clamping (CC) at birth may have been commonly discouraged despite a lack of convincing evidence of mother-to-neonate SARS-CoV-2 transmission. We aimed to systematically review guidelines, reports of practice and to analyze associations between timing of cord clamping and mother-to-neonate SARS-CoV-2 transmission during the early phases of the pandemic.
METHODS: Major databases were searched December 1, 2019 to July 20, 2021.
INCLUSION: studies and guidelines describing cord clamping practice in women with SARS-CoV-2 infection during pregnancy until two postnatal days, giving birth to live born neonates.
EXCLUSION: no extractable data. Two... (More)
OBJECTIVES: In the beginning of the COVID-19 pandemic, delayed umbilical cord clamping (CC) at birth may have been commonly discouraged despite a lack of convincing evidence of mother-to-neonate SARS-CoV-2 transmission. We aimed to systematically review guidelines, reports of practice and to analyze associations between timing of cord clamping and mother-to-neonate SARS-CoV-2 transmission during the early phases of the pandemic.
METHODS: Major databases were searched December 1, 2019 to July 20, 2021.
INCLUSION: studies and guidelines describing cord clamping practice in women with SARS-CoV-2 infection during pregnancy until two postnatal days, giving birth to live born neonates.
EXCLUSION: no extractable data. Two reviewers independently screened studies for eligibility and assessed study quality. Pooled prevalence rates were calculated.
RESULTS: Forty-eight studies (1476 neonates) and 40 guidelines were included. Delayed CC was recommended in 70.0% of the guidelines. Nevertheless, delayed CC was reported less often than early CC: 262/1476 (17.8%) vs. 511/1476 (34.6%). Neonatal SARS-CoV-2 positivity rates were similar following delayed (1.2%) and early CC (1.3%). Most SARS-CoV-2 transmissions (93.3%) occurred in utero.
CONCLUSION: Delayed CC did not seem to increase mother-to-neonate SARS-CoV-2 transmission. Due to its benefits, it should be encouraged even in births where the mother has a SARS-CoV-2 infection.
(Less)
- author
- Berg, Johan
LU
; Thies-Lagergren, Li
LU
; Svedenkrans, Jenny
LU
; Samkutty, Jeremiah
; Larsson, Sara Marie
LU
; Mercer, Judith S
; Rabe, Heike
; Andersson, Ola
LU
and Zaigham, Mehreen
LU
- organization
- publishing date
- 2023-10-13
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Journal of Infectious Diseases
- volume
- 137
- pages
- 63 - 70
- publisher
- Elsevier
- external identifiers
-
- scopus:85175161254
- pmid:37839504
- ISSN
- 1878-3511
- DOI
- 10.1016/j.ijid.2023.10.010
- project
- The effects of pre-, peri- and postnatal factors on the infant’s health and neurodevelopment
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2023. Published by Elsevier Ltd.
- id
- c6a075bf-1a72-423e-9e56-da64a0f393db
- date added to LUP
- 2023-10-16 16:51:55
- date last changed
- 2024-11-01 22:18:37
@article{c6a075bf-1a72-423e-9e56-da64a0f393db,
abstract = {{<p>OBJECTIVES: In the beginning of the COVID-19 pandemic, delayed umbilical cord clamping (CC) at birth may have been commonly discouraged despite a lack of convincing evidence of mother-to-neonate SARS-CoV-2 transmission. We aimed to systematically review guidelines, reports of practice and to analyze associations between timing of cord clamping and mother-to-neonate SARS-CoV-2 transmission during the early phases of the pandemic.</p><p>METHODS: Major databases were searched December 1, 2019 to July 20, 2021.</p><p>INCLUSION: studies and guidelines describing cord clamping practice in women with SARS-CoV-2 infection during pregnancy until two postnatal days, giving birth to live born neonates.</p><p>EXCLUSION: no extractable data. Two reviewers independently screened studies for eligibility and assessed study quality. Pooled prevalence rates were calculated.</p><p>RESULTS: Forty-eight studies (1476 neonates) and 40 guidelines were included. Delayed CC was recommended in 70.0% of the guidelines. Nevertheless, delayed CC was reported less often than early CC: 262/1476 (17.8%) vs. 511/1476 (34.6%). Neonatal SARS-CoV-2 positivity rates were similar following delayed (1.2%) and early CC (1.3%). Most SARS-CoV-2 transmissions (93.3%) occurred in utero.</p><p>CONCLUSION: Delayed CC did not seem to increase mother-to-neonate SARS-CoV-2 transmission. Due to its benefits, it should be encouraged even in births where the mother has a SARS-CoV-2 infection.</p>}},
author = {{Berg, Johan and Thies-Lagergren, Li and Svedenkrans, Jenny and Samkutty, Jeremiah and Larsson, Sara Marie and Mercer, Judith S and Rabe, Heike and Andersson, Ola and Zaigham, Mehreen}},
issn = {{1878-3511}},
language = {{eng}},
month = {{10}},
pages = {{63--70}},
publisher = {{Elsevier}},
series = {{International Journal of Infectious Diseases}},
title = {{Umbilical cord clamping in the early phases of the COVID-19 era - A systematic review and meta-analysis of reported practice and recommendations in guidelines}},
url = {{http://dx.doi.org/10.1016/j.ijid.2023.10.010}},
doi = {{10.1016/j.ijid.2023.10.010}},
volume = {{137}},
year = {{2023}},
}