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Transcranial direct current stimulation based on quantitative electroencephalogram combining positive psychotherapy for major depression

Khayyer, Zahra; Ngaosuvan, Leonard; Sikström, Sverker LU and Ghaderi, Amir Hossein (2018) In Journal of Integrative Neuroscience 17(2). p.141-155
Abstract (Swedish)
Abstract. Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions 29 participants with clinical depression; (a) tDCS therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale (HDRS), Adult State Hope Scale and Optimism/Pessimism Scale (OPS) was used at baseline, 2 weeks, 4-weeks and 3-months follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and... (More)
Abstract. Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions 29 participants with clinical depression; (a) tDCS therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale (HDRS), Adult State Hope Scale and Optimism/Pessimism Scale (OPS) was used at baseline, 2 weeks, 4-weeks and 3-months follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after 4-weeks as well as during 3-months follow-up than the other conditions. The results are discussed 32 in terms of additive or synergistic relation between tDCS and PP treatment. Future studies should (a) use larger sample-sizes,
(b) include no-treatment control conditions, (c) include double-blind designs, (d) control for previous or on-going drug therapy, (d) control for previous or ongoing psychotherapy. Furthermore, future studies should aim to increase theoretical understanding by investigating whether the relation between tDCS and psychotherapy are additive or synergistic. (Less)
Abstract
Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions participants with clinical depression; (a) tDCS therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale (HDRS), Adult State Hope Scale and Optimism/Pessimism Scale (OPS) was used at baseline, 2 weeks, 4-weeks and 3-months follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after... (More)
Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions participants with clinical depression; (a) tDCS therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale (HDRS), Adult State Hope Scale and Optimism/Pessimism Scale (OPS) was used at baseline, 2 weeks, 4-weeks and 3-months follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after 4-weeks as well as during 3-months follow-up than the other conditions. The results are discussed in terms of additive or synergistic relation between tDCS and PP treatment. Future studies should (a) use larger sample-sizes, (b) include no-treatment control conditions, (c) include double-blind designs, (d) control for previous or on-going drug therapy, (d) control for previous or ongoing psychotherapy. Furthermore, future studies should aim to increase theoretical understanding by investigating whether the relation between tDCS and psychotherapy are additive or synergistic. (Less)
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author
organization
alternative title
Transkraniell likströmsstimulering baserad på kvantitativt elektroencefalogram som kombinerar positiv psykoterapi och depression
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Case study, major depression, transcranial direct current stimulation (tDCS), quantitative electroencephalogram (qEEG), positive psychotherapy
in
Journal of Integrative Neuroscience
volume
17
issue
2
pages
15 pages
external identifiers
  • scopus:85043342367
DOI
10.3233/JIN-170045
language
English
LU publication?
yes
id
c93e8834-08a4-4042-aa5a-804724b75839
date added to LUP
2017-10-13 11:22:28
date last changed
2018-04-14 03:00:08
@article{c93e8834-08a4-4042-aa5a-804724b75839,
  abstract     = {Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions participants with clinical depression; (a) tDCS therapy, (b) positive psychotherapy, and (c) combined treatment. Hamilton Depression Rating Scale (HDRS), Adult State Hope Scale and Optimism/Pessimism Scale (OPS) was used at baseline, 2 weeks, 4-weeks and 3-months follow-up. Combined condition participants showed greater reduction in depressed mood, improved hope and optimism after 4-weeks as well as during 3-months follow-up than the other conditions. The results are discussed in terms of additive or synergistic relation between tDCS and PP treatment. Future studies should (a) use larger sample-sizes, (b) include no-treatment control conditions, (c) include double-blind designs, (d) control for previous or on-going drug therapy, (d) control for previous or ongoing psychotherapy. Furthermore, future studies should aim to increase theoretical understanding by investigating whether the relation between tDCS and psychotherapy are additive or synergistic.},
  author       = {Khayyer, Zahra and Ngaosuvan, Leonard and Sikström, Sverker and Ghaderi, Amir Hossein },
  keyword      = {Case study, major depression, transcranial direct current stimulation (tDCS), quantitative electroencephalogram (qEEG), positive psychotherapy},
  language     = {eng},
  month        = {03},
  number       = {2},
  pages        = {141--155},
  series       = {Journal of Integrative Neuroscience},
  title        = {Transcranial direct current stimulation based on quantitative electroencephalogram combining positive psychotherapy for major depression},
  url          = {http://dx.doi.org/10.3233/JIN-170045},
  volume       = {17},
  year         = {2018},
}