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The effect of endoscopic sinus surgery on quality of life and absenteeism in patients with chronic rhinosinuitis - A multi-centre study

Sahlstrand-Johnson, Pernilla LU ; Hopkins, Claire; Ohlsson, Bodil LU and Ahlner-Elmqvist, Marianne LU (2017) In Rhinology 55(3). p.251-261
Abstract

Background: Chronic rhinosinusitis with and without nasal polyps (CRSw/sNP) are common conditions decreasing health-related quality of life (HRQOL). Individual symptoms capable of predicting outcome after endoscopic sinus surgery (ESS) are poorly defined, and the indirect costs of CRS is rarely reported in Europe. Methodology: Patients with CRSw/sNP admitted for ESS were prospectively enrolled. Patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), a Visual Analogue Scale (VAS) and reported CRS-related absenteeism pre- and post-operatively. Results: 181 patients were included. The SNOT-22 score diminished from 51.8 (48.7–55.0) pre-operatively to 33.0 (29.2–36.8) at 6 months. 64%... (More)

Background: Chronic rhinosinusitis with and without nasal polyps (CRSw/sNP) are common conditions decreasing health-related quality of life (HRQOL). Individual symptoms capable of predicting outcome after endoscopic sinus surgery (ESS) are poorly defined, and the indirect costs of CRS is rarely reported in Europe. Methodology: Patients with CRSw/sNP admitted for ESS were prospectively enrolled. Patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), a Visual Analogue Scale (VAS) and reported CRS-related absenteeism pre- and post-operatively. Results: 181 patients were included. The SNOT-22 score diminished from 51.8 (48.7–55.0) pre-operatively to 33.0 (29.2–36.8) at 6 months. 64% achieved a clinically important improvement in the SNOT-22. SF-36 scores improved statistically significantly in all domains except “Role Emotional”. The VAS score halved from 68 (65–71) to 34 (29–39) at 6 months post-operatively. A pre-operative SNOT-22 score >20 implied a greater chance of score improvement after 6 months. A multivariate model identified individual items associated with SNOT-22. Further, patients that had <12 months of sinus disease derived greatest benefit. CRS-related absenteeism dropped from 8–14 days to 1–7 days 12 months after ESS. Conclusions: This prospective study showed that ESS significantly improved the HRQOL and decreased absenteeism of patients with CRSw/sNP. Shorter duration of disease and “Need to blow nose” and “Blockage/congestion of nose” of SNOT-22 were identified as predictive factors for good surgical outcome.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Absenteeism, Chronic rhinosinusitis, Nasal polyps, Outcome, Quality of life, Sinus surgery
in
Rhinology
volume
55
issue
3
pages
11 pages
publisher
International Rhinologic Society
external identifiers
  • scopus:85029393334
ISSN
0300-0729
DOI
10.4193/Rhino16.126
language
English
LU publication?
yes
id
c9a4625b-cd6c-49c6-b0be-094da551fefb
date added to LUP
2017-10-06 12:22:44
date last changed
2018-04-15 04:47:47
@article{c9a4625b-cd6c-49c6-b0be-094da551fefb,
  abstract     = {<p>Background: Chronic rhinosinusitis with and without nasal polyps (CRSw/sNP) are common conditions decreasing health-related quality of life (HRQOL). Individual symptoms capable of predicting outcome after endoscopic sinus surgery (ESS) are poorly defined, and the indirect costs of CRS is rarely reported in Europe. Methodology: Patients with CRSw/sNP admitted for ESS were prospectively enrolled. Patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), a Visual Analogue Scale (VAS) and reported CRS-related absenteeism pre- and post-operatively. Results: 181 patients were included. The SNOT-22 score diminished from 51.8 (48.7–55.0) pre-operatively to 33.0 (29.2–36.8) at 6 months. 64% achieved a clinically important improvement in the SNOT-22. SF-36 scores improved statistically significantly in all domains except “Role Emotional”. The VAS score halved from 68 (65–71) to 34 (29–39) at 6 months post-operatively. A pre-operative SNOT-22 score &gt;20 implied a greater chance of score improvement after 6 months. A multivariate model identified individual items associated with SNOT-22. Further, patients that had &lt;12 months of sinus disease derived greatest benefit. CRS-related absenteeism dropped from 8–14 days to 1–7 days 12 months after ESS. Conclusions: This prospective study showed that ESS significantly improved the HRQOL and decreased absenteeism of patients with CRSw/sNP. Shorter duration of disease and “Need to blow nose” and “Blockage/congestion of nose” of SNOT-22 were identified as predictive factors for good surgical outcome.</p>},
  author       = {Sahlstrand-Johnson, Pernilla and Hopkins, Claire and Ohlsson, Bodil and Ahlner-Elmqvist, Marianne},
  issn         = {0300-0729},
  keyword      = {Absenteeism,Chronic rhinosinusitis,Nasal polyps,Outcome,Quality of life,Sinus surgery},
  language     = {eng},
  number       = {3},
  pages        = {251--261},
  publisher    = {International Rhinologic Society},
  series       = {Rhinology},
  title        = {The effect of endoscopic sinus surgery on quality of life and absenteeism in patients with chronic rhinosinuitis - A multi-centre study},
  url          = {http://dx.doi.org/10.4193/Rhino16.126},
  volume       = {55},
  year         = {2017},
}