Effects of working memory load and CS-US intervals on delay eyeblink conditioning
Etemadi, Leila LU ; Jirenhed, Dan Anders LU and Rasmussen, Anders LU
(2023)
In npj Science of Learning
8.
p.1-5
- Abstract
Eyeblink conditioning is used in many species to study motor learning and make inferences about cerebellar function. However, the discrepancies in performance between humans and other species combined with evidence that volition and awareness can modulate learning suggest that eyeblink conditioning is not merely a passive form of learning that relies on only the cerebellum. Here we explored two ways to reduce the influence of volition and awareness on eyeblink conditioning: (1) using a short interstimulus interval, and (2) having participants do working memory tasks during the conditioning. Our results show that participants trained with short interstimulus intervals (150 ms and 250 ms) produce very few conditioned responses after 100... (More)
Eyeblink conditioning is used in many species to study motor learning and make inferences about cerebellar function. However, the discrepancies in performance between humans and other species combined with evidence that volition and awareness can modulate learning suggest that eyeblink conditioning is not merely a passive form of learning that relies on only the cerebellum. Here we explored two ways to reduce the influence of volition and awareness on eyeblink conditioning: (1) using a short interstimulus interval, and (2) having participants do working memory tasks during the conditioning. Our results show that participants trained with short interstimulus intervals (150 ms and 250 ms) produce very few conditioned responses after 100 trials. Participants trained with a longer interstimulus interval (500 ms) who simultaneously did working memory tasks produced fewer conditioned responses than participants who watched a movie during the training. Our results suggest that having participants perform working memory tasks during eyeblink conditioning can be a viable strategy for studying cerebellar learning that is absent of influences from awareness and volition. This could enhance the comparability of the results obtained in human studies with those in animal models.
(Less)
- author
- Etemadi, Leila
LU
; Jirenhed, Dan Anders
LU
and Rasmussen, Anders
LU
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- in
- npj Science of Learning
- volume
- 8
- article number
- 16
- pages
- 1 - 5
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:37210441
- scopus:85160074545
- ISSN
- 2056-7936
- DOI
- 10.1038/s41539-023-00167-w
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2023, The Author(s).
- id
- cbd1d760-ae77-45b0-b47e-576b7b7e7607
- date added to LUP
- 2023-06-09 20:51:49
- date last changed
- 2024-04-19 22:43:26
@article{cbd1d760-ae77-45b0-b47e-576b7b7e7607,
abstract = {{<p>Eyeblink conditioning is used in many species to study motor learning and make inferences about cerebellar function. However, the discrepancies in performance between humans and other species combined with evidence that volition and awareness can modulate learning suggest that eyeblink conditioning is not merely a passive form of learning that relies on only the cerebellum. Here we explored two ways to reduce the influence of volition and awareness on eyeblink conditioning: (1) using a short interstimulus interval, and (2) having participants do working memory tasks during the conditioning. Our results show that participants trained with short interstimulus intervals (150 ms and 250 ms) produce very few conditioned responses after 100 trials. Participants trained with a longer interstimulus interval (500 ms) who simultaneously did working memory tasks produced fewer conditioned responses than participants who watched a movie during the training. Our results suggest that having participants perform working memory tasks during eyeblink conditioning can be a viable strategy for studying cerebellar learning that is absent of influences from awareness and volition. This could enhance the comparability of the results obtained in human studies with those in animal models.</p>}},
author = {{Etemadi, Leila and Jirenhed, Dan Anders and Rasmussen, Anders}},
issn = {{2056-7936}},
language = {{eng}},
pages = {{1--5}},
publisher = {{Nature Publishing Group}},
series = {{npj Science of Learning}},
title = {{Effects of working memory load and CS-US intervals on delay eyeblink conditioning}},
url = {{http://dx.doi.org/10.1038/s41539-023-00167-w}},
doi = {{10.1038/s41539-023-00167-w}},
volume = {{8}},
year = {{2023}},
}