New directions of miniaturization within the proteomics research area
(2003) In Electrophoresis 24(21). p.3521-3532- Abstract
- An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/294619
- author
- Marko-Varga, György LU ; Nilsson, Johan LU and Laurell, Thomas LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- proteomics, miniaturization, protein expression profiling, review
- in
- Electrophoresis
- volume
- 24
- issue
- 21
- pages
- 3521 - 3532
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000186858700002
- pmid:14613179
- scopus:0347764579
- ISSN
- 0173-0835
- DOI
- 10.1002/elps.200305666
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biomedical Engineering (011200011), Analytical Chemistry (S/LTH) (011001004)
- id
- ced33133-61e6-4a21-85dd-dd8475cb61f5 (old id 294619)
- date added to LUP
- 2016-04-01 12:29:51
- date last changed
- 2022-01-27 05:54:12
@article{ced33133-61e6-4a21-85dd-dd8475cb61f5, abstract = {{An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.}}, author = {{Marko-Varga, György and Nilsson, Johan and Laurell, Thomas}}, issn = {{0173-0835}}, keywords = {{proteomics; miniaturization; protein expression profiling; review}}, language = {{eng}}, number = {{21}}, pages = {{3521--3532}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Electrophoresis}}, title = {{New directions of miniaturization within the proteomics research area}}, url = {{http://dx.doi.org/10.1002/elps.200305666}}, doi = {{10.1002/elps.200305666}}, volume = {{24}}, year = {{2003}}, }