The Menstrual Cycle and Risk of Breast Cancer : A Review
(2020) In Frontiers in Oncology 10.- Abstract
Cyclic hormonal stimulation of the breast tissue plays a significant role in breast carcinogenesis. Current risk factor models do not include direct measures of cycle characteristics although the effects of possible surrogates of cycle activity such as age at menarche and menopause, parity, and nursing time have been investigated. Future risk models should also include menstrual cycle length, regularity, number of cycles before first full-term pregnancy, and life-time number of cycles. New risk factor models for pre- and postmenopausal breast cancer are proposed here. Furthermore, there is a need for more long-term, prospective studies investigating menstrual cycle characteristics as data currently available are primarily retrospective... (More)
Cyclic hormonal stimulation of the breast tissue plays a significant role in breast carcinogenesis. Current risk factor models do not include direct measures of cycle characteristics although the effects of possible surrogates of cycle activity such as age at menarche and menopause, parity, and nursing time have been investigated. Future risk models should also include menstrual cycle length, regularity, number of cycles before first full-term pregnancy, and life-time number of cycles. New risk factor models for pre- and postmenopausal breast cancer are proposed here. Furthermore, there is a need for more long-term, prospective studies investigating menstrual cycle characteristics as data currently available are primarily retrospective and collected at one time-point only.
(Less)
- author
- Olsson, Håkan Lars LU and Olsson, Mona Landin LU
- organization
- publishing date
- 2020-01-24
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- breast cancer, menstrual cycle, prospective, retrospective, risk
- in
- Frontiers in Oncology
- volume
- 10
- article number
- 21
- publisher
- Frontiers Media S. A.
- external identifiers
-
- scopus:85079158470
- pmid:32038990
- ISSN
- 2234-943X
- DOI
- 10.3389/fonc.2020.00021
- language
- English
- LU publication?
- yes
- id
- d0f5dcda-db94-4607-a659-28d4a21bcc14
- date added to LUP
- 2020-02-20 15:22:52
- date last changed
- 2024-03-20 05:01:08
@article{d0f5dcda-db94-4607-a659-28d4a21bcc14, abstract = {{<p>Cyclic hormonal stimulation of the breast tissue plays a significant role in breast carcinogenesis. Current risk factor models do not include direct measures of cycle characteristics although the effects of possible surrogates of cycle activity such as age at menarche and menopause, parity, and nursing time have been investigated. Future risk models should also include menstrual cycle length, regularity, number of cycles before first full-term pregnancy, and life-time number of cycles. New risk factor models for pre- and postmenopausal breast cancer are proposed here. Furthermore, there is a need for more long-term, prospective studies investigating menstrual cycle characteristics as data currently available are primarily retrospective and collected at one time-point only.</p>}}, author = {{Olsson, Håkan Lars and Olsson, Mona Landin}}, issn = {{2234-943X}}, keywords = {{breast cancer; menstrual cycle; prospective; retrospective; risk}}, language = {{eng}}, month = {{01}}, publisher = {{Frontiers Media S. A.}}, series = {{Frontiers in Oncology}}, title = {{The Menstrual Cycle and Risk of Breast Cancer : A Review}}, url = {{http://dx.doi.org/10.3389/fonc.2020.00021}}, doi = {{10.3389/fonc.2020.00021}}, volume = {{10}}, year = {{2020}}, }