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Patients With Intermittent Claudication and Chronic Widespread Pain Improves in Health-Related Quality of Life After Invasive but Not After Noninvasive Treatment

Lindgren, Hans I.V. LU ; Pärsson, Håkan LU ; Gottsäter, Anders LU and Bergman, Stefan LU (2017) In Clinical Medicine Insights: Cardiology 11.
Abstract

Background: Intermittent claudication (IC) is traditionally managed with risk factor modification, best medical treatment (BMT), and exercise training. Comorbidities such as diabetes and ischemic heart disease affect both results of invasive treatment and health-related quality of life (HRQoL) negatively. It is unknown how chronic widespread pain (CWP) influences the results of invasive treatment. We evaluated the influence of CWP on HRQoL in patients undergoing invasive (open surgery or endovascular treatment) and noninvasive BMT of IC. Methods: A total of 242 patients with IC treated with invasive or noninvasive methods responded to the validated HRQoL questionnaires Short Form 36 Health Survey, EuroQoL 5-dimensions, and distribution... (More)

Background: Intermittent claudication (IC) is traditionally managed with risk factor modification, best medical treatment (BMT), and exercise training. Comorbidities such as diabetes and ischemic heart disease affect both results of invasive treatment and health-related quality of life (HRQoL) negatively. It is unknown how chronic widespread pain (CWP) influences the results of invasive treatment. We evaluated the influence of CWP on HRQoL in patients undergoing invasive (open surgery or endovascular treatment) and noninvasive BMT of IC. Methods: A total of 242 patients with IC treated with invasive or noninvasive methods responded to the validated HRQoL questionnaires Short Form 36 Health Survey, EuroQoL 5-dimensions, and distribution of pain with the Epipain questionnaire at baseline and after 12 months. Results: Invasively treated patients without CWP improved in all primary outcome measures. Patients with CWP reported significant improvements in most of the HRQoL-related outcome measures after invasive treatment, but patients with CWP in the noninvasive treatment group did not improve in any HRQoL-related outcome measure. Conclusions: The presence of CWP not should be a cause to withhold invasive treatment in patients with IC.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
chronic pain, HRQoL, Intermittent Claudication, invasive treatment
in
Clinical Medicine Insights: Cardiology
volume
11
publisher
SAGE Publications
external identifiers
  • scopus:85044626858
  • pmid:29308018
ISSN
1179-5468
DOI
10.1177/1179546817747528
language
English
LU publication?
yes
id
d31117c6-0849-4134-bbf7-390d5fd879d8
date added to LUP
2018-04-12 16:06:18
date last changed
2024-05-13 08:28:13
@article{d31117c6-0849-4134-bbf7-390d5fd879d8,
  abstract     = {{<p>Background: Intermittent claudication (IC) is traditionally managed with risk factor modification, best medical treatment (BMT), and exercise training. Comorbidities such as diabetes and ischemic heart disease affect both results of invasive treatment and health-related quality of life (HRQoL) negatively. It is unknown how chronic widespread pain (CWP) influences the results of invasive treatment. We evaluated the influence of CWP on HRQoL in patients undergoing invasive (open surgery or endovascular treatment) and noninvasive BMT of IC. Methods: A total of 242 patients with IC treated with invasive or noninvasive methods responded to the validated HRQoL questionnaires Short Form 36 Health Survey, EuroQoL 5-dimensions, and distribution of pain with the Epipain questionnaire at baseline and after 12 months. Results: Invasively treated patients without CWP improved in all primary outcome measures. Patients with CWP reported significant improvements in most of the HRQoL-related outcome measures after invasive treatment, but patients with CWP in the noninvasive treatment group did not improve in any HRQoL-related outcome measure. Conclusions: The presence of CWP not should be a cause to withhold invasive treatment in patients with IC.</p>}},
  author       = {{Lindgren, Hans I.V. and Pärsson, Håkan and Gottsäter, Anders and Bergman, Stefan}},
  issn         = {{1179-5468}},
  keywords     = {{chronic pain; HRQoL; Intermittent Claudication; invasive treatment}},
  language     = {{eng}},
  month        = {{12}},
  publisher    = {{SAGE Publications}},
  series       = {{Clinical Medicine Insights: Cardiology}},
  title        = {{Patients With Intermittent Claudication and Chronic Widespread Pain Improves in Health-Related Quality of Life After Invasive but Not After Noninvasive Treatment}},
  url          = {{http://dx.doi.org/10.1177/1179546817747528}},
  doi          = {{10.1177/1179546817747528}},
  volume       = {{11}},
  year         = {{2017}},
}