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Eight-year outcome after invasive treatment of infrainguinal intermittent claudication : A population-based analysis from the Swedish vascular register (Swedvasc)

Gunnarsson, Thordur LU ; Gottsäter, Anders LU ; Bergman, Stefan ; Troëng, Thomas and Lindgren, Hans LU (2020) In SAGE Open Medicine 8.
Abstract

Objectives: Invasive treatment of infrainguinal intermittent claudication is controversial, and long-term outcomes are scarce. The study aim was to evaluate 8 years results regarding new vascular interventions on index and contralateral limb, hospitalization, mortality, and amputation in 775 patients revascularized for infrainguinal intermittent claudication in 2009. Methods: Data on new vascular interventions retrieved from the Swedish vascular register (Swedvasc) were linked to the Inpatient Register and Cause of Death Register with information on hospitalizations, primary discharge diagnoses according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10), deaths, causes... (More)

Objectives: Invasive treatment of infrainguinal intermittent claudication is controversial, and long-term outcomes are scarce. The study aim was to evaluate 8 years results regarding new vascular interventions on index and contralateral limb, hospitalization, mortality, and amputation in 775 patients revascularized for infrainguinal intermittent claudication in 2009. Methods: Data on new vascular interventions retrieved from the Swedish vascular register (Swedvasc) were linked to the Inpatient Register and Cause of Death Register with information on hospitalizations, primary discharge diagnoses according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10), deaths, causes of death, and amputations. Results: During 8 years of follow-up, 486 new vascular interventions were performed. Patients were admitted for a total of 4662 hospitalizations and spent 25,970 days in hospital. Between 79% and 99% of surviving subjects were hospitalized each year. During follow-up, 311 (40.1%) patients died. The most common causes of hospitalization and death were cerebrovascular disease, ischemic heart disease, or other diseases of the circulatory system, causing 47.5% of hospitalizations and 42.4% of deaths. Seventy-seven major lower limb amputations were performed in 52 patients. Conclusion: As patients undergoing invasive treatment of infrainguinal intermittent claudication have high morbidity and mortality, during 8 years of follow-up, the indication for invasive treatment should be carefully weighed against concomitant comorbidities and the timing of this treatment optimized with regard to the patient’s possibilities to enjoy positive treatment effects on quality of life.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cardiovascular, intermittent claudication, invasive treatment, long-term follow-up, Surgery
in
SAGE Open Medicine
volume
8
publisher
SAGE Publications
external identifiers
  • scopus:85147490649
ISSN
2050-3121
DOI
10.1177/2050312120926782
language
English
LU publication?
yes
id
d49727ae-7836-45fd-8318-a79c8521cb63
date added to LUP
2023-02-20 15:39:56
date last changed
2023-02-20 15:39:56
@article{d49727ae-7836-45fd-8318-a79c8521cb63,
  abstract     = {{<p>Objectives: Invasive treatment of infrainguinal intermittent claudication is controversial, and long-term outcomes are scarce. The study aim was to evaluate 8 years results regarding new vascular interventions on index and contralateral limb, hospitalization, mortality, and amputation in 775 patients revascularized for infrainguinal intermittent claudication in 2009. Methods: Data on new vascular interventions retrieved from the Swedish vascular register (Swedvasc) were linked to the Inpatient Register and Cause of Death Register with information on hospitalizations, primary discharge diagnoses according to the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10), deaths, causes of death, and amputations. Results: During 8 years of follow-up, 486 new vascular interventions were performed. Patients were admitted for a total of 4662 hospitalizations and spent 25,970 days in hospital. Between 79% and 99% of surviving subjects were hospitalized each year. During follow-up, 311 (40.1%) patients died. The most common causes of hospitalization and death were cerebrovascular disease, ischemic heart disease, or other diseases of the circulatory system, causing 47.5% of hospitalizations and 42.4% of deaths. Seventy-seven major lower limb amputations were performed in 52 patients. Conclusion: As patients undergoing invasive treatment of infrainguinal intermittent claudication have high morbidity and mortality, during 8 years of follow-up, the indication for invasive treatment should be carefully weighed against concomitant comorbidities and the timing of this treatment optimized with regard to the patient’s possibilities to enjoy positive treatment effects on quality of life.</p>}},
  author       = {{Gunnarsson, Thordur and Gottsäter, Anders and Bergman, Stefan and Troëng, Thomas and Lindgren, Hans}},
  issn         = {{2050-3121}},
  keywords     = {{cardiovascular; intermittent claudication; invasive treatment; long-term follow-up; Surgery}},
  language     = {{eng}},
  publisher    = {{SAGE Publications}},
  series       = {{SAGE Open Medicine}},
  title        = {{Eight-year outcome after invasive treatment of infrainguinal intermittent claudication : A population-based analysis from the Swedish vascular register (Swedvasc)}},
  url          = {{http://dx.doi.org/10.1177/2050312120926782}},
  doi          = {{10.1177/2050312120926782}},
  volume       = {{8}},
  year         = {{2020}},
}