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Sociodemographic factors associated with HbA1c variability in type 2 diabetes: a prospective exploratory cohort study

Mellergård, Emelia LU ; Johnsson, Per LU and Eek, Frida LU (2020) In BMC Endocrine Disorders 20.
Abstract
Background
The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics related to diabetes management. The present study examined differences in baseline HbA1c and HbA1c variability between groups with regard to sex, level of education, civil status, age, and BMI, in a sample of individuals with type 2 diabetes.

Methods
The study was a prospective exploratory cohort study. Differences in HbA1c variability between sociodemographic groups were analyzed in 158 individuals. HbA1c variability was assessed as the standard deviation (SD) and coefficient of variation (CV) over five... (More)
Background
The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics related to diabetes management. The present study examined differences in baseline HbA1c and HbA1c variability between groups with regard to sex, level of education, civil status, age, and BMI, in a sample of individuals with type 2 diabetes.

Methods
The study was a prospective exploratory cohort study. Differences in HbA1c variability between sociodemographic groups were analyzed in 158 individuals. HbA1c variability was assessed as the standard deviation (SD) and coefficient of variation (CV) over five measured points, and a questionnaire was used to assess sociodemographic factors.

Results
The results showed significantly higher HbA1c variability in men compared to women (mean difference 1.44 mmol/mol [95% CI: 0.58 to 2.31]), and significantly higher HbA1c variability in individuals with a BMI characterized as obese compared to individuals with a BMI characterized as normal weight (mean difference 1.56 mmol/mol [95% CI: 0.25 to 2.88]). There were no significant associations between HbA1c variability and civil status or education.

Conclusions
Men and individuals with obesity may be more vulnerable to future diabetic complications than other groups, since they have greater long-term glycemic variability. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Type 2 Diabetes, Glycemic control, HbA1c variability, Sociodemographic factors, Sex differences, BMI, Diabetes management
in
BMC Endocrine Disorders
volume
20
article number
102
pages
8 pages
publisher
BioMed Central (BMC)
external identifiers
  • scopus:85087725302
  • pmid:32641021
ISSN
1472-6823
DOI
10.1186/s12902-020-00585-6
language
English
LU publication?
yes
id
d50a824d-d11f-4ed3-ac0c-b2b474bc31cb
date added to LUP
2020-07-16 10:17:21
date last changed
2022-04-18 23:31:07
@article{d50a824d-d11f-4ed3-ac0c-b2b474bc31cb,
  abstract     = {{Background<br/>The associations between sociodemographic factors and HbA1c variability in type 2 diabetes are not yet established. Examining group differences in HbA1c variability may help identify patient characteristics related to diabetes management. The present study examined differences in baseline HbA1c and HbA1c variability between groups with regard to sex, level of education, civil status, age, and BMI, in a sample of individuals with type 2 diabetes.<br/><br/>Methods<br/>The study was a prospective exploratory cohort study. Differences in HbA1c variability between sociodemographic groups were analyzed in 158 individuals. HbA1c variability was assessed as the standard deviation (SD) and coefficient of variation (CV) over five measured points, and a questionnaire was used to assess sociodemographic factors.<br/><br/>Results<br/>The results showed significantly higher HbA1c variability in men compared to women (mean difference 1.44 mmol/mol [95% CI: 0.58 to 2.31]), and significantly higher HbA1c variability in individuals with a BMI characterized as obese compared to individuals with a BMI characterized as normal weight (mean difference 1.56 mmol/mol [95% CI: 0.25 to 2.88]). There were no significant associations between HbA1c variability and civil status or education.<br/><br/>Conclusions<br/>Men and individuals with obesity may be more vulnerable to future diabetic complications than other groups, since they have greater long-term glycemic variability.}},
  author       = {{Mellergård, Emelia and Johnsson, Per and Eek, Frida}},
  issn         = {{1472-6823}},
  keywords     = {{Type 2 Diabetes; Glycemic control; HbA1c variability; Sociodemographic factors; Sex differences; BMI; Diabetes management}},
  language     = {{eng}},
  month        = {{07}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Endocrine Disorders}},
  title        = {{Sociodemographic factors associated with HbA1c variability in type 2 diabetes: a prospective exploratory cohort study}},
  url          = {{http://dx.doi.org/10.1186/s12902-020-00585-6}},
  doi          = {{10.1186/s12902-020-00585-6}},
  volume       = {{20}},
  year         = {{2020}},
}