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The yield of screening symptomatic contacts of multidrug-resistant tuberculosis cases at a tertiary hospital in Addis Ababa, Ethiopia.

Titiyos, A ; Jerene, Degu LU and Enquselassie, F (2015) In BMC Research Notes 8. p.1-6
Abstract
Background
Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.
Results
Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced... (More)
Background
Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.
Results
Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced of whom 16 (10 %) had confirmed MDR-TB. At least one confirmed MDR-TB cases was identified in 15 (51.7 %) of the 29 traced households.
Conclusions
Tracing symptomatic contacts of MDR-TB cases could be a high yield strategy for early detection and treatment of MDR-TB cases in the community. The approach should be promoted for wider adoption and dissemination. Larger scale studies should be done to determine its effectiveness and sustainability in similar settings.
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author
; and
publishing date
type
Contribution to journal
publication status
published
in
BMC Research Notes
volume
8
article number
501
pages
1 - 6
publisher
BioMed Central (BMC)
external identifiers
  • scopus:84942802076
ISSN
1756-0500
DOI
10.1186/s13104-015-1442-z
project
LUC3 - Lund University Child Centered Care
language
English
LU publication?
no
id
d51f3c14-6359-47b4-9720-f2e1246a54f3
date added to LUP
2019-06-28 10:55:16
date last changed
2022-03-10 18:25:02
@article{d51f3c14-6359-47b4-9720-f2e1246a54f3,
  abstract     = {{Background<br/>Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.<br/>Results<br/>Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced of whom 16 (10 %) had confirmed MDR-TB. At least one confirmed MDR-TB cases was identified in 15 (51.7 %) of the 29 traced households.<br/>Conclusions<br/>Tracing symptomatic contacts of MDR-TB cases could be a high yield strategy for early detection and treatment of MDR-TB cases in the community. The approach should be promoted for wider adoption and dissemination. Larger scale studies should be done to determine its effectiveness and sustainability in similar settings.<br/>}},
  author       = {{Titiyos, A and Jerene, Degu and Enquselassie, F}},
  issn         = {{1756-0500}},
  language     = {{eng}},
  pages        = {{1--6}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Research Notes}},
  title        = {{The yield of screening symptomatic contacts of multidrug-resistant tuberculosis cases at a tertiary hospital in Addis Ababa, Ethiopia.}},
  url          = {{http://dx.doi.org/10.1186/s13104-015-1442-z}},
  doi          = {{10.1186/s13104-015-1442-z}},
  volume       = {{8}},
  year         = {{2015}},
}