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Complicated COVID-19 in pregnancy : a case report with severe liver and coagulation dysfunction promptly improved by delivery

Ronnje, Louise LU ; Länsberg, John-Kalle LU ; Vikhareva, Olga LU ; Hansson, Stefan R LU orcid ; Herbst, Andreas LU and Zaigham, Mehreen LU orcid (2020) In BMC Pregnancy and Childbirth 20(1). p.511-511
Abstract

BACKGROUND: It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infection.

CASE PRESENTATION: A 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough, myalgia, nausea, abdominal pain and fever. A nasopharyngeal swab returned positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Her condition... (More)

BACKGROUND: It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infection.

CASE PRESENTATION: A 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough, myalgia, nausea, abdominal pain and fever. A nasopharyngeal swab returned positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Her condition rapidly worsened leading to severe liver and coagulation impairment. An emergency Caesarean section was performed at gestational week 32 + 6 after which the patient made a rapid recovery. Severe COVID-19 promptly improved by the termination of the pregnancy or atypical HELLP (Hemolysis, Elevated Liver Enzymes and Low Platelet Count) exacerbated by concomitant COVID-19 infection could not be ruled out. There was no evidence of vertical transmission.

CONCLUSIONS: This case adds to the growing body of evidence which raises concerns about the possible negative maternal outcomes of COVID-19 infection during pregnancy and advocates for pregnant women to be recognized as a vulnerable group during the current pandemic.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Pregnancy and Childbirth
volume
20
issue
1
pages
511 - 511
publisher
BioMed Central (BMC)
external identifiers
  • pmid:32887569
  • scopus:85088248270
ISSN
1471-2393
DOI
10.1186/s12884-020-03172-8
language
English
LU publication?
yes
id
d73dc0ee-9d7f-4548-84c7-cb325e91b689
date added to LUP
2020-09-09 08:41:36
date last changed
2024-05-29 19:21:24
@article{d73dc0ee-9d7f-4548-84c7-cb325e91b689,
  abstract     = {{<p>BACKGROUND: It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From the few case series that are available in the literature, women with high risk pregnancies have been associated with higher morbidity. It has been suggested that pregnancy induced immune responses and cardio-vascular changes can exaggerate the course of the COVID-19 infection.</p><p>CASE PRESENTATION: A 26-year old Somalian woman (G2P1) presented with a nine-day history of shortness of breath, dry cough, myalgia, nausea, abdominal pain and fever. A nasopharyngeal swab returned positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Her condition rapidly worsened leading to severe liver and coagulation impairment. An emergency Caesarean section was performed at gestational week 32 + 6 after which the patient made a rapid recovery. Severe COVID-19 promptly improved by the termination of the pregnancy or atypical HELLP (Hemolysis, Elevated Liver Enzymes and Low Platelet Count) exacerbated by concomitant COVID-19 infection could not be ruled out. There was no evidence of vertical transmission.</p><p>CONCLUSIONS: This case adds to the growing body of evidence which raises concerns about the possible negative maternal outcomes of COVID-19 infection during pregnancy and advocates for pregnant women to be recognized as a vulnerable group during the current pandemic.</p>}},
  author       = {{Ronnje, Louise and Länsberg, John-Kalle and Vikhareva, Olga and Hansson, Stefan R and Herbst, Andreas and Zaigham, Mehreen}},
  issn         = {{1471-2393}},
  language     = {{eng}},
  month        = {{09}},
  number       = {{1}},
  pages        = {{511--511}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Pregnancy and Childbirth}},
  title        = {{Complicated COVID-19 in pregnancy : a case report with severe liver and coagulation dysfunction promptly improved by delivery}},
  url          = {{http://dx.doi.org/10.1186/s12884-020-03172-8}},
  doi          = {{10.1186/s12884-020-03172-8}},
  volume       = {{20}},
  year         = {{2020}},
}