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Coordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU) : Concepts, procedures and lessons learnt

Vorkamp, Katrin ; Esteban López, Marta ; Gilles, Liese ; Göen, Thomas ; Govarts, Eva ; Hajeb, Parvaneh ; Katsonouri, Andromachi ; Knudsen, Lisbeth E. ; Kolossa-Gehring, Marike and Lindh, Christian LU orcid , et al. (2023) In International Journal of Hygiene and Environmental Health 251.
Abstract

The European Human Biomonitoring Initiative (HBM4EU) ran from 2017 to 2022 with the aim of advancing and harmonizing human biomonitoring in Europe. More than 40,000 analyses were performed on human samples in different human biomonitoring studies in HBM4EU, addressing the chemical exposure of the general population, temporal developments, occupational exposure and a public health intervention on mercury in populations with high fish consumption. The analyses covered 15 priority groups of organic chemicals and metals and were carried out by a network of laboratories meeting the requirements of a comprehensive quality assurance and control system. The coordination of the chemical analyses included establishing contacts between sample... (More)

The European Human Biomonitoring Initiative (HBM4EU) ran from 2017 to 2022 with the aim of advancing and harmonizing human biomonitoring in Europe. More than 40,000 analyses were performed on human samples in different human biomonitoring studies in HBM4EU, addressing the chemical exposure of the general population, temporal developments, occupational exposure and a public health intervention on mercury in populations with high fish consumption. The analyses covered 15 priority groups of organic chemicals and metals and were carried out by a network of laboratories meeting the requirements of a comprehensive quality assurance and control system. The coordination of the chemical analyses included establishing contacts between sample owners and qualified laboratories and monitoring the progress of the chemical analyses during the analytical phase, also addressing status and consequences of Covid-19 measures. Other challenges were related to the novelty and complexity of HBM4EU, including administrative and financial matters and implementation of standardized procedures. Many individual contacts were necessary in the initial phase of HBM4EU. However, there is a potential to develop more streamlined and standardized communication and coordination in the analytical phase of a consolidated European HBM programme.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aligned Studies, Analytical phase, Exposure, Human biomonitoring (HBM), Laboratory network, Quality assurance and control (QA/QC)
in
International Journal of Hygiene and Environmental Health
volume
251
article number
114183
publisher
Elsevier
external identifiers
  • pmid:37148759
  • scopus:85154572128
ISSN
1438-4639
DOI
10.1016/j.ijheh.2023.114183
language
English
LU publication?
yes
id
d76e3f96-8bcc-43c4-8e96-aef1fec5a992
date added to LUP
2023-06-20 14:34:47
date last changed
2024-04-19 23:01:07
@article{d76e3f96-8bcc-43c4-8e96-aef1fec5a992,
  abstract     = {{<p>The European Human Biomonitoring Initiative (HBM4EU) ran from 2017 to 2022 with the aim of advancing and harmonizing human biomonitoring in Europe. More than 40,000 analyses were performed on human samples in different human biomonitoring studies in HBM4EU, addressing the chemical exposure of the general population, temporal developments, occupational exposure and a public health intervention on mercury in populations with high fish consumption. The analyses covered 15 priority groups of organic chemicals and metals and were carried out by a network of laboratories meeting the requirements of a comprehensive quality assurance and control system. The coordination of the chemical analyses included establishing contacts between sample owners and qualified laboratories and monitoring the progress of the chemical analyses during the analytical phase, also addressing status and consequences of Covid-19 measures. Other challenges were related to the novelty and complexity of HBM4EU, including administrative and financial matters and implementation of standardized procedures. Many individual contacts were necessary in the initial phase of HBM4EU. However, there is a potential to develop more streamlined and standardized communication and coordination in the analytical phase of a consolidated European HBM programme.</p>}},
  author       = {{Vorkamp, Katrin and Esteban López, Marta and Gilles, Liese and Göen, Thomas and Govarts, Eva and Hajeb, Parvaneh and Katsonouri, Andromachi and Knudsen, Lisbeth E. and Kolossa-Gehring, Marike and Lindh, Christian and Nübler, Stefanie and Pedraza-Díaz, Susana and Santonen, Tiina and Castaño, Argelia}},
  issn         = {{1438-4639}},
  keywords     = {{Aligned Studies; Analytical phase; Exposure; Human biomonitoring (HBM); Laboratory network; Quality assurance and control (QA/QC)}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{International Journal of Hygiene and Environmental Health}},
  title        = {{Coordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU) : Concepts, procedures and lessons learnt}},
  url          = {{http://dx.doi.org/10.1016/j.ijheh.2023.114183}},
  doi          = {{10.1016/j.ijheh.2023.114183}},
  volume       = {{251}},
  year         = {{2023}},
}