Carpal Tunnel Syndrome and Trigger Finger May Be an Early Symptom of Preclinic Type 2 Diabetes
Rydberg, Mattias LU
; Perez, Raquel
LU
; Merlo, Juan
LU
and Dahlin, Lars B
LU
(2024)
In Plastic and reconstructive surgery. Global open
12(6).
p.1-7
- Abstract
BACKGROUND: Type 2 diabetes (T2D) is a major risk factor for carpal tunnel syndrome (CTS) and trigger finger (TF), but less is known regarding the risk of developing T2D after being diagnosed with CTS or TF. CTS and TF could be early signs of preclinical T2D, and early detection of T2D is crucial to prevent complications and morbidity. Therefore, we investigate the association between CTS/TF and T2D in an adult population without previous T2D using big data registers in Sweden.
METHODS: Data were collected by crosslinking five nationwide Swedish registers. Individuals aged 40-85 years on December 31, 2010, without prior overt diabetes, were included (n = 3,948,517) and followed up from baseline (ie, a diagnosis of CTS or TF) or... (More)
BACKGROUND: Type 2 diabetes (T2D) is a major risk factor for carpal tunnel syndrome (CTS) and trigger finger (TF), but less is known regarding the risk of developing T2D after being diagnosed with CTS or TF. CTS and TF could be early signs of preclinical T2D, and early detection of T2D is crucial to prevent complications and morbidity. Therefore, we investigate the association between CTS/TF and T2D in an adult population without previous T2D using big data registers in Sweden.
METHODS: Data were collected by crosslinking five nationwide Swedish registers. Individuals aged 40-85 years on December 31, 2010, without prior overt diabetes, were included (n = 3,948,517) and followed up from baseline (ie, a diagnosis of CTS or TF) or January 1, 2011, for controls, until a diagnosis of T2D, prescription of oral antidiabetics or insulin, or end of follow-up four years after baseline. Multivariate Cox regression models were created to calculate hazard ratios for T2D.
RESULTS: In total, 37,346 (0.95%) patients were diagnosed with CTS, whereof 1329 (3.46%) developed T2D. There were 17,432 (0.44%) patients who developed TF, whereof 639 (3.67%) developed T2D. Among the controls, 2.73% developed T2D. Compared with controls, there was an increased risk of developing T2D after being diagnosed with either CTS (HR 1.35; 95% confidence interval 1.28-1.43) or TF (HR 1.21; 95% confidence interval 1.12-1.31).
CONCLUSION: Compared with controls, a diagnosis of CTS or TF was associated with 35% and 21% higher risk for later T2D, respectively, which might indicate the existence of undetected T2D in this population.
(Less)
- author
- Rydberg, Mattias
LU
; Perez, Raquel
LU
; Merlo, Juan
LU
and Dahlin, Lars B
LU
- organization
- publishing date
- 2024-06
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Plastic and reconstructive surgery. Global open
- volume
- 12
- issue
- 6
- article number
- e5907
- pages
- 1 - 7
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:38881965
- scopus:85196733036
- ISSN
- 2169-7574
- DOI
- 10.1097/GOX.0000000000005907
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.
- id
- d7b4844e-3a39-456f-a0bf-355d687e1e63
- date added to LUP
- 2024-07-01 10:15:04
- date last changed
- 2024-07-03 02:50:49
@article{d7b4844e-3a39-456f-a0bf-355d687e1e63,
abstract = {{<p>BACKGROUND: Type 2 diabetes (T2D) is a major risk factor for carpal tunnel syndrome (CTS) and trigger finger (TF), but less is known regarding the risk of developing T2D after being diagnosed with CTS or TF. CTS and TF could be early signs of preclinical T2D, and early detection of T2D is crucial to prevent complications and morbidity. Therefore, we investigate the association between CTS/TF and T2D in an adult population without previous T2D using big data registers in Sweden.</p><p>METHODS: Data were collected by crosslinking five nationwide Swedish registers. Individuals aged 40-85 years on December 31, 2010, without prior overt diabetes, were included (n = 3,948,517) and followed up from baseline (ie, a diagnosis of CTS or TF) or January 1, 2011, for controls, until a diagnosis of T2D, prescription of oral antidiabetics or insulin, or end of follow-up four years after baseline. Multivariate Cox regression models were created to calculate hazard ratios for T2D.</p><p>RESULTS: In total, 37,346 (0.95%) patients were diagnosed with CTS, whereof 1329 (3.46%) developed T2D. There were 17,432 (0.44%) patients who developed TF, whereof 639 (3.67%) developed T2D. Among the controls, 2.73% developed T2D. Compared with controls, there was an increased risk of developing T2D after being diagnosed with either CTS (HR 1.35; 95% confidence interval 1.28-1.43) or TF (HR 1.21; 95% confidence interval 1.12-1.31).</p><p>CONCLUSION: Compared with controls, a diagnosis of CTS or TF was associated with 35% and 21% higher risk for later T2D, respectively, which might indicate the existence of undetected T2D in this population.</p>}},
author = {{Rydberg, Mattias and Perez, Raquel and Merlo, Juan and Dahlin, Lars B}},
issn = {{2169-7574}},
language = {{eng}},
number = {{6}},
pages = {{1--7}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Plastic and reconstructive surgery. Global open}},
title = {{Carpal Tunnel Syndrome and Trigger Finger May Be an Early Symptom of Preclinic Type 2 Diabetes}},
url = {{http://dx.doi.org/10.1097/GOX.0000000000005907}},
doi = {{10.1097/GOX.0000000000005907}},
volume = {{12}},
year = {{2024}},
}