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A novel semi-automatic hip morphology assessment tool is more accurate than manual radiographic evaluations

Khayyeri, Hanifeh LU ; Väänänen, Sami P.; Flivik, Gunnar LU ; Jurvelin, Jukka S.; Dahlberg, Leif LU and Isaksson, Hanna LU (2019) In Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization
Abstract

Radiological and pathological characteristics of hip osteoarthritis (OA) is joint-space loss due to degradation of articular cartilage. However, patients with early-stage OA do not yet show any radiological signs, which leaves them without diagnosis and treatment. This study evaluates the potential of a novel tool to identify pre-radiographic OA changes based on hip bone morphology. Two statistical appearance models for femur and pelvis were used to estimate the 3Dmorphology of the hip bones based on planar radiographs from patients. Well-known hip geometrical parameters (n = 22) were computed from patient CT scans (truth), 3D reconstructions (new method) and radiographs (calculated manually). The methods were compared by measuring... (More)

Radiological and pathological characteristics of hip osteoarthritis (OA) is joint-space loss due to degradation of articular cartilage. However, patients with early-stage OA do not yet show any radiological signs, which leaves them without diagnosis and treatment. This study evaluates the potential of a novel tool to identify pre-radiographic OA changes based on hip bone morphology. Two statistical appearance models for femur and pelvis were used to estimate the 3Dmorphology of the hip bones based on planar radiographs from patients. Well-known hip geometrical parameters (n = 22) were computed from patient CT scans (truth), 3D reconstructions (new method) and radiographs (calculated manually). The methods were compared by measuring relative error to truth. The new method was significantly more accurate in calculating hip geometrical parameters than the manual 2D calculations. The proposed approach could also capture rotational parameters like cross-over sign and anterior wall sign (100% correct predictions). The method can successfully reconstruct 3D hip shapes and densities for patients that have not yet developed severe osteoarthritis, and provided higher precision than manual estimations. Thus, it may be used to calculate morphological parameters that are predictors of OA and can become a powerful tool in human hip OA research and diagnostics.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
diagnostics, hip morphology, Hip osteoarthritis, Statistical Appearance Model
in
Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization
publisher
Taylor & Francis
external identifiers
  • scopus:85062357001
ISSN
2168-1163
DOI
10.1080/21681163.2019.1578266
language
English
LU publication?
yes
id
d84a09d3-b27e-4cdf-9c9c-d26f64af5ea0
date added to LUP
2019-03-14 10:50:21
date last changed
2019-04-10 04:20:58
@article{d84a09d3-b27e-4cdf-9c9c-d26f64af5ea0,
  abstract     = {<p>Radiological and pathological characteristics of hip osteoarthritis (OA) is joint-space loss due to degradation of articular cartilage. However, patients with early-stage OA do not yet show any radiological signs, which leaves them without diagnosis and treatment. This study evaluates the potential of a novel tool to identify pre-radiographic OA changes based on hip bone morphology. Two statistical appearance models for femur and pelvis were used to estimate the 3Dmorphology of the hip bones based on planar radiographs from patients. Well-known hip geometrical parameters (n = 22) were computed from patient CT scans (truth), 3D reconstructions (new method) and radiographs (calculated manually). The methods were compared by measuring relative error to truth. The new method was significantly more accurate in calculating hip geometrical parameters than the manual 2D calculations. The proposed approach could also capture rotational parameters like cross-over sign and anterior wall sign (100% correct predictions). The method can successfully reconstruct 3D hip shapes and densities for patients that have not yet developed severe osteoarthritis, and provided higher precision than manual estimations. Thus, it may be used to calculate morphological parameters that are predictors of OA and can become a powerful tool in human hip OA research and diagnostics.</p>},
  author       = {Khayyeri, Hanifeh and Väänänen, Sami P. and Flivik, Gunnar and Jurvelin, Jukka S. and Dahlberg, Leif and Isaksson, Hanna},
  issn         = {2168-1163},
  keyword      = {diagnostics,hip morphology,Hip osteoarthritis,Statistical Appearance Model},
  language     = {eng},
  month        = {02},
  publisher    = {Taylor & Francis},
  series       = {Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization},
  title        = {A novel semi-automatic hip morphology assessment tool is more accurate than manual radiographic evaluations},
  url          = {http://dx.doi.org/10.1080/21681163.2019.1578266},
  year         = {2019},
}