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Musculoskeletal health and frailty

McGuigan, Fiona E. LU ; Bartosch, Patrik LU and Åkesson, Kristina E. LU (2017) In Best Practice and Research: Clinical Rheumatology 31(2). p.145-159
Abstract

Frailty is a consequence of advanced aging, where the frailty phenotype tries to capture overall decline in health. Frailty involves multiple physiological systems that are intrinsically inter-related and with highly complex interactions. Frailty is closely linked to musculoskeletal health; musculoskeletal functioning is a key component in quantifying frailty, while at the same time, frailty is associated with the most common age-related musculoskeletal conditions: osteoporosis, fractures, falls, osteoarthritis, and spinal conditions. Beyond that, frailty includes additional physical domains such as nutrition and energy, psychological, and social factors. Despite its recognized role in aging health, there is still a lack of consensus on... (More)

Frailty is a consequence of advanced aging, where the frailty phenotype tries to capture overall decline in health. Frailty involves multiple physiological systems that are intrinsically inter-related and with highly complex interactions. Frailty is closely linked to musculoskeletal health; musculoskeletal functioning is a key component in quantifying frailty, while at the same time, frailty is associated with the most common age-related musculoskeletal conditions: osteoporosis, fractures, falls, osteoarthritis, and spinal conditions. Beyond that, frailty includes additional physical domains such as nutrition and energy, psychological, and social factors. Despite its recognized role in aging health, there is still a lack of consensus on a core set of variables and how to best define clinically relevant thresholds. This would be of utmost importance for additional use to evaluate many aspects associated with musculoskeletal health, progression and personalized interventions, and rehabilitation.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Elderly, Fracture, Frailty, Index, Osteoarthritis
in
Best Practice and Research: Clinical Rheumatology
volume
31
issue
2
pages
15 pages
publisher
Baillière Tindall
external identifiers
  • scopus:85034097391
ISSN
1521-6942
DOI
10.1016/j.berh.2017.11.002
language
English
LU publication?
yes
id
d87490b5-b76f-43f5-afbd-5b6dad6316d7
date added to LUP
2017-12-21 13:55:03
date last changed
2018-01-07 12:29:43
@article{d87490b5-b76f-43f5-afbd-5b6dad6316d7,
  abstract     = {<p>Frailty is a consequence of advanced aging, where the frailty phenotype tries to capture overall decline in health. Frailty involves multiple physiological systems that are intrinsically inter-related and with highly complex interactions. Frailty is closely linked to musculoskeletal health; musculoskeletal functioning is a key component in quantifying frailty, while at the same time, frailty is associated with the most common age-related musculoskeletal conditions: osteoporosis, fractures, falls, osteoarthritis, and spinal conditions. Beyond that, frailty includes additional physical domains such as nutrition and energy, psychological, and social factors. Despite its recognized role in aging health, there is still a lack of consensus on a core set of variables and how to best define clinically relevant thresholds. This would be of utmost importance for additional use to evaluate many aspects associated with musculoskeletal health, progression and personalized interventions, and rehabilitation.</p>},
  author       = {McGuigan, Fiona E. and Bartosch, Patrik and Åkesson, Kristina E.},
  issn         = {1521-6942},
  keyword      = {Elderly,Fracture,Frailty,Index,Osteoarthritis},
  language     = {eng},
  month        = {04},
  number       = {2},
  pages        = {145--159},
  publisher    = {Baillière Tindall},
  series       = {Best Practice and Research: Clinical Rheumatology},
  title        = {Musculoskeletal health and frailty},
  url          = {http://dx.doi.org/10.1016/j.berh.2017.11.002},
  volume       = {31},
  year         = {2017},
}