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Granulocyte Colony-Stimulating Factor in Patients With Acute Ischemic Stroke: Results of the AX200 for Ischemic Stroke Trial.

Ringelstein, E Bernd ; Thijs, Vincent ; Norrving, Bo LU ; Chamorro, Angel ; Aichner, Franz ; Grond, Martin ; Saver, Jeff ; Laage, Rico ; Schneider, Armin and Rathgeb, Frank , et al. (2013) In Stroke: a journal of cerebral circulation 44(10). p.2681-2687
Abstract
Granulocyte colony-stimulating factor (G-CSF; AX200; Filgrastim) is a stroke drug candidate with excellent preclinical evidence for efficacy. A previous phase IIa dose-escalation study suggested potential efficacy in humans. The present large phase IIb trial was powered to detect clinical efficacy in acute ischemic stroke patients.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Stroke: a journal of cerebral circulation
volume
44
issue
10
pages
2681 - 2687
publisher
American Heart Association
external identifiers
  • wos:000324831900018
  • pmid:23963331
  • scopus:84888309505
  • pmid:23963331
ISSN
1524-4628
DOI
10.1161/STROKEAHA.113.001531
language
English
LU publication?
yes
id
d9833583-81c2-4bd2-a380-8e2da4b04190 (old id 4005444)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23963331?dopt=Abstract
date added to LUP
2016-04-01 09:53:26
date last changed
2022-03-04 05:58:10
@article{d9833583-81c2-4bd2-a380-8e2da4b04190,
  abstract     = {{Granulocyte colony-stimulating factor (G-CSF; AX200; Filgrastim) is a stroke drug candidate with excellent preclinical evidence for efficacy. A previous phase IIa dose-escalation study suggested potential efficacy in humans. The present large phase IIb trial was powered to detect clinical efficacy in acute ischemic stroke patients.}},
  author       = {{Ringelstein, E Bernd and Thijs, Vincent and Norrving, Bo and Chamorro, Angel and Aichner, Franz and Grond, Martin and Saver, Jeff and Laage, Rico and Schneider, Armin and Rathgeb, Frank and Vogt, Gerhard and Charissé, Gabriele and Fiebach, Jochen B and Schwab, Stefan and Schäbitz, Wolf R and Kollmar, Rainer and Fisher, Marc and Brozman, Miroslav and Skoloudik, David and Gruber, Franz and Leal, Joaquin Serena and Veltkamp, Roland and Köhrmann, Martin and Berrouschot, Jörg}},
  issn         = {{1524-4628}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{2681--2687}},
  publisher    = {{American Heart Association}},
  series       = {{Stroke: a journal of cerebral circulation}},
  title        = {{Granulocyte Colony-Stimulating Factor in Patients With Acute Ischemic Stroke: Results of the AX200 for Ischemic Stroke Trial.}},
  url          = {{http://dx.doi.org/10.1161/STROKEAHA.113.001531}},
  doi          = {{10.1161/STROKEAHA.113.001531}},
  volume       = {{44}},
  year         = {{2013}},
}