Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones.
Eberhardt, Jacob LU ; Persson, Bertil R LU
; Brun, Arne
LU
; Salford, Leif
LU
and Malmgren, Lars O G
(2008)
In Electromagnetic Biology and Medicine
27(3).
p.215-229
- Abstract
- We investigated the effects of global system for mobile communication (GSM) microwave exposure on the permeability of the blood-brain barrier and signs of neuronal damage in rats using a real GSM programmable mobile phone in the 900 MHz band. Ninety-six non-anaesthetized rats were either exposed to microwaves or sham exposed in TEM-cells for 2 h at specific absorption rates of average whole-body Specific Absorption Rates (SAR) of 0.12, 1.2, 12, or 120 mW/kg. The rats were sacrificed after a recovery time of either 14 or 28 d, following exposure and the extravazation of albumin, its uptake into neurons, and occurrence of damaged neurons was assessed. Albumin extravazation and also its uptake into neurons was seen to be enhanced after 14 d... (More)
- We investigated the effects of global system for mobile communication (GSM) microwave exposure on the permeability of the blood-brain barrier and signs of neuronal damage in rats using a real GSM programmable mobile phone in the 900 MHz band. Ninety-six non-anaesthetized rats were either exposed to microwaves or sham exposed in TEM-cells for 2 h at specific absorption rates of average whole-body Specific Absorption Rates (SAR) of 0.12, 1.2, 12, or 120 mW/kg. The rats were sacrificed after a recovery time of either 14 or 28 d, following exposure and the extravazation of albumin, its uptake into neurons, and occurrence of damaged neurons was assessed. Albumin extravazation and also its uptake into neurons was seen to be enhanced after 14 d (Kruskal Wallis test: p = 0.02 and 0.002, respectively), but not after a 28 d recovery period. The occurrence of dark neurons in the rat brains, on the other hand, was enhanced later, after 28 d (p = 0.02). Furthermore, in the 28-d brain samples, neuronal albumin uptake was significantly correlated to occurrence of damaged neurons (Spearman r = 0.41; p < 0.01). (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1262772
- author
- Eberhardt, Jacob
LU
; Persson, Bertil R
LU
; Brun, Arne
LU
; Salford, Leif
LU
and Malmgren, Lars O G
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Electromagnetic Biology and Medicine
- volume
- 27
- issue
- 3
- pages
- 215 - 229
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000259541300002
- pmid:18821198
- scopus:52949091992
- pmid:18821198
- ISSN
- 1536-8386
- DOI
- 10.1080/15368370802344037
- language
- English
- LU publication?
- yes
- id
- dcb5db30-8c76-437c-8c24-10e73f4ede53 (old id 1262772)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18821198?dopt=Abstract
- date added to LUP
- 2016-04-04 08:11:54
- date last changed
- 2022-03-15 07:46:48
@article{dcb5db30-8c76-437c-8c24-10e73f4ede53,
abstract = {{We investigated the effects of global system for mobile communication (GSM) microwave exposure on the permeability of the blood-brain barrier and signs of neuronal damage in rats using a real GSM programmable mobile phone in the 900 MHz band. Ninety-six non-anaesthetized rats were either exposed to microwaves or sham exposed in TEM-cells for 2 h at specific absorption rates of average whole-body Specific Absorption Rates (SAR) of 0.12, 1.2, 12, or 120 mW/kg. The rats were sacrificed after a recovery time of either 14 or 28 d, following exposure and the extravazation of albumin, its uptake into neurons, and occurrence of damaged neurons was assessed. Albumin extravazation and also its uptake into neurons was seen to be enhanced after 14 d (Kruskal Wallis test: p = 0.02 and 0.002, respectively), but not after a 28 d recovery period. The occurrence of dark neurons in the rat brains, on the other hand, was enhanced later, after 28 d (p = 0.02). Furthermore, in the 28-d brain samples, neuronal albumin uptake was significantly correlated to occurrence of damaged neurons (Spearman r = 0.41; p < 0.01).}},
author = {{Eberhardt, Jacob and Persson, Bertil R and Brun, Arne and Salford, Leif and Malmgren, Lars O G}},
issn = {{1536-8386}},
language = {{eng}},
number = {{3}},
pages = {{215--229}},
publisher = {{Informa Healthcare}},
series = {{Electromagnetic Biology and Medicine}},
title = {{Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM mobile phones.}},
url = {{http://dx.doi.org/10.1080/15368370802344037}},
doi = {{10.1080/15368370802344037}},
volume = {{27}},
year = {{2008}},
}