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Factors important for health-related quality of life in men and women: The population based SCAPIS study

Olsson, Max LU orcid ; Björkelund, Anders J. LU ; Sandberg, Jacob LU orcid ; Blomberg, Anders ; Börjesson, Mats ; Currow, David ; Malinovschi, Andrei ; Sköld, Magnus ; Wollmer, Per LU and Torén, Kjell , et al. (2023) In PLoS ONE 18(11).
Abstract
Introduction
Health-related quality of life (HRQoL) is essential for human wellbeing, influenced by a complex interplay of factors, and is reported lower in women than men. We aimed to evaluate which factors were the most important for HRQoL in a middle-aged general population.
Methods
This was a cross-sectional, multi-centre study of 29,212 men (48%) and women (52%) aged 50–64 in the general population in Sweden. Physical and mental HRQoL (0–100) was assessed using the Short Form 12 questionnaire, and association was evaluated for 356 variables including demographics, lifestyle, symptoms, physiological measurements, and health conditions. Using machine learning, each variable´s importance for HRQoL was measured by an... (More)
Introduction
Health-related quality of life (HRQoL) is essential for human wellbeing, influenced by a complex interplay of factors, and is reported lower in women than men. We aimed to evaluate which factors were the most important for HRQoL in a middle-aged general population.
Methods
This was a cross-sectional, multi-centre study of 29,212 men (48%) and women (52%) aged 50–64 in the general population in Sweden. Physical and mental HRQoL (0–100) was assessed using the Short Form 12 questionnaire, and association was evaluated for 356 variables including demographics, lifestyle, symptoms, physiological measurements, and health conditions. Using machine learning, each variable´s importance for HRQoL was measured by an importance score, comparable to effect size, and summarised in 54 factors, in men and women separately.
Results
Men and women had similar mean and standard deviation (SD) scores for physical HRQoL (53.4 [SD 8.1] vs 51.4 [9.7]) and mental HRQoL (37.1 [5.0] vs 37.3 [5.4]). The most important factors for physical HRQoL were (importance score) physical activity (40), employment (36), pain (33), sleep (33), and sense of control (26). The most important factors for mental HRQoL were sense of control (18), physical activity (12), depression (12), pain (6), and employment (5).
Conclusions
The factors important for HRQoL identified by this study are likely to be amenable to interventions, and our findings can support prioritising interventions. The identified factors need to be a target even before middle-age to lay the foundation for long and happy lives.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
livskvalitet
in
PLoS ONE
volume
18
issue
11
article number
e0294030
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:37922283
  • scopus:85176006546
ISSN
1932-6203
DOI
10.1371/journal.pone.0294030
project
AIR Lund - Artificially Intelligent use of Registers
language
English
LU publication?
yes
id
dce597e3-b0f9-4881-8d09-ba2e0f53954b
date added to LUP
2023-11-06 10:34:24
date last changed
2024-04-17 13:26:26
@article{dce597e3-b0f9-4881-8d09-ba2e0f53954b,
  abstract     = {{Introduction<br/>Health-related quality of life (HRQoL) is essential for human wellbeing, influenced by a complex interplay of factors, and is reported lower in women than men. We aimed to evaluate which factors were the most important for HRQoL in a middle-aged general population.<br/>Methods<br/>This was a cross-sectional, multi-centre study of 29,212 men (48%) and women (52%) aged 50–64 in the general population in Sweden. Physical and mental HRQoL (0–100) was assessed using the Short Form 12 questionnaire, and association was evaluated for 356 variables including demographics, lifestyle, symptoms, physiological measurements, and health conditions. Using machine learning, each variable´s importance for HRQoL was measured by an importance score, comparable to effect size, and summarised in 54 factors, in men and women separately.<br/>Results<br/>Men and women had similar mean and standard deviation (SD) scores for physical HRQoL (53.4 [SD 8.1] vs 51.4 [9.7]) and mental HRQoL (37.1 [5.0] vs 37.3 [5.4]). The most important factors for physical HRQoL were (importance score) physical activity (40), employment (36), pain (33), sleep (33), and sense of control (26). The most important factors for mental HRQoL were sense of control (18), physical activity (12), depression (12), pain (6), and employment (5).<br/>Conclusions<br/>The factors important for HRQoL identified by this study are likely to be amenable to interventions, and our findings can support prioritising interventions. The identified factors need to be a target even before middle-age to lay the foundation for long and happy lives.<br/>}},
  author       = {{Olsson, Max and Björkelund, Anders J. and Sandberg, Jacob and Blomberg, Anders and Börjesson, Mats and Currow, David and Malinovschi, Andrei and Sköld, Magnus and Wollmer, Per and Torén, Kjell and Östgren, Carl-johan and Engström, Gunnar and Ekström, Magnus}},
  issn         = {{1932-6203}},
  keywords     = {{livskvalitet}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{11}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Factors important for health-related quality of life in men and women: The population based SCAPIS study}},
  url          = {{http://dx.doi.org/10.1371/journal.pone.0294030}},
  doi          = {{10.1371/journal.pone.0294030}},
  volume       = {{18}},
  year         = {{2023}},
}