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Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease

Ingvar, Åsa M LU orcid ; Olsson, Håkan LU orcid ; Broberg, Per LU ; Isaksson, Karolin LU ; Ingvar, Christian LU and Nielsen, Kari LU orcid (2020) In Acta Dermato-Venereologica 100(1).
Abstract

Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma compared with non-participants and the background population. Information was collected from Swedish National Registers on participants (n = 30,501) and non-participants (n = 10,499) in the "Melanoma In Southern Sweden" (MISS) study and the background population (n = 243,032). Hazard ratios were calculated for overall incidence of cancer and melanoma, and all-cause and melanoma-specific mortality, using Cox regression. Participants had a... (More)

Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma compared with non-participants and the background population. Information was collected from Swedish National Registers on participants (n = 30,501) and non-participants (n = 10,499) in the "Melanoma In Southern Sweden" (MISS) study and the background population (n = 243,032). Hazard ratios were calculated for overall incidence of cancer and melanoma, and all-cause and melanoma-specific mortality, using Cox regression. Participants had a lower overall incidence of cancer and all-cause mortality than non-participants and the background population. There was no difference in incidence of melanoma or melanoma-specific characteristics between participants and the background population. In conclusion, participants in the MISS study have a slightly better general health, but are a representative sample of the population with regard to studies of melanoma risk factors.

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Dermato-Venereologica
volume
100
issue
1
article number
adv00010
publisher
Medical Journals Limited
external identifiers
  • scopus:85077875013
  • pmid:31663602
ISSN
1651-2057
DOI
10.2340/00015555-3362
project
MISS (Melanoma in Southern Sweden) population based cohort of 40 000 women
language
English
LU publication?
yes
id
e1d486dc-0d2e-4f48-b547-d6542d967ba0
date added to LUP
2020-01-10 12:56:00
date last changed
2025-01-10 05:28:33
@article{e1d486dc-0d2e-4f48-b547-d6542d967ba0,
  abstract     = {{<p>Prospective observational studies have shown previously that study participants have lower morbidity and mortality than non-participants. The aim of the current study was to determine whether participants in a prospective cohort study on melanoma have a different incidence and mortality of melanoma compared with non-participants and the background population. Information was collected from Swedish National Registers on participants (n = 30,501) and non-participants (n = 10,499) in the "Melanoma In Southern Sweden" (MISS) study and the background population (n = 243,032). Hazard ratios were calculated for overall incidence of cancer and melanoma, and all-cause and melanoma-specific mortality, using Cox regression. Participants had a lower overall incidence of cancer and all-cause mortality than non-participants and the background population. There was no difference in incidence of melanoma or melanoma-specific characteristics between participants and the background population. In conclusion, participants in the MISS study have a slightly better general health, but are a representative sample of the population with regard to studies of melanoma risk factors.</p>}},
  author       = {{Ingvar, Åsa M and Olsson, Håkan and Broberg, Per and Isaksson, Karolin and Ingvar, Christian and Nielsen, Kari}},
  issn         = {{1651-2057}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Participation in a Prospective Cohort Study on Melanoma did not Affect the Incidence and Mortality of the Studied Disease}},
  url          = {{http://dx.doi.org/10.2340/00015555-3362}},
  doi          = {{10.2340/00015555-3362}},
  volume       = {{100}},
  year         = {{2020}},
}