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The relationship of optokinetic nystagmus to pursuit eye movements, vestibular nystagmus and to saccades in humans. A clinical study

Magnusson, M LU ; Pyykkö, I. and Norrving, B LU (1986) In Acta oto-laryngologica 101(5-6). p.70-361
Abstract

The relationship of mean velocity of optokinetic nystagmus (OKN) to pursuit eye movements (PEM), to vestibular nystagmus and to voluntary saccades was analysed in 10 patients with peripheral vestibular lesions and in 30 patients with central vestibular lesions. PEM and vestibular nystagmus were significantly correlated to OKN, suggesting that a common neural pathway is used in the generation of these eye movements. Weak or no correlation was found between saccadic peak velocity and slow phase velocity of OKN. Using multiple linear regression analysis, it was found that 78.5% of the variation in the slow-phase velocity of OKN could be explained by a synthesis of PEM and vestibular test data. PEM test data were more powerful than those of... (More)

The relationship of mean velocity of optokinetic nystagmus (OKN) to pursuit eye movements (PEM), to vestibular nystagmus and to voluntary saccades was analysed in 10 patients with peripheral vestibular lesions and in 30 patients with central vestibular lesions. PEM and vestibular nystagmus were significantly correlated to OKN, suggesting that a common neural pathway is used in the generation of these eye movements. Weak or no correlation was found between saccadic peak velocity and slow phase velocity of OKN. Using multiple linear regression analysis, it was found that 78.5% of the variation in the slow-phase velocity of OKN could be explained by a synthesis of PEM and vestibular test data. PEM test data were more powerful than those of vestibular nystagmus in deduction of OKN. The possible appearance of slow build-up of OKN could not be deduced from the reduction of PEM. Hence, the relationship between PEM and OKN in man is not a simple linear one, but is more complex.

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keywords
Adolescent, Adult, Aged, Electrooculography, Eye Movements, Humans, Labyrinth Diseases, Middle Aged, Neural Pathways, Nystagmus, Physiologic, Regression Analysis, Saccades, Vestibular Function Tests, Vestibule, Labyrinth, Journal Article
in
Acta oto-laryngologica
volume
101
issue
5-6
pages
10 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0022656697
ISSN
0001-6489
language
English
LU publication?
yes
id
e375d6ff-f97d-4db5-8217-b4395e7f2df1
date added to LUP
2017-05-03 13:06:33
date last changed
2017-06-07 14:13:55
@article{e375d6ff-f97d-4db5-8217-b4395e7f2df1,
  abstract     = {<p>The relationship of mean velocity of optokinetic nystagmus (OKN) to pursuit eye movements (PEM), to vestibular nystagmus and to voluntary saccades was analysed in 10 patients with peripheral vestibular lesions and in 30 patients with central vestibular lesions. PEM and vestibular nystagmus were significantly correlated to OKN, suggesting that a common neural pathway is used in the generation of these eye movements. Weak or no correlation was found between saccadic peak velocity and slow phase velocity of OKN. Using multiple linear regression analysis, it was found that 78.5% of the variation in the slow-phase velocity of OKN could be explained by a synthesis of PEM and vestibular test data. PEM test data were more powerful than those of vestibular nystagmus in deduction of OKN. The possible appearance of slow build-up of OKN could not be deduced from the reduction of PEM. Hence, the relationship between PEM and OKN in man is not a simple linear one, but is more complex.</p>},
  author       = {Magnusson, M and Pyykkö, I. and Norrving, B},
  issn         = {0001-6489},
  keyword      = {Adolescent,Adult,Aged,Electrooculography,Eye Movements,Humans,Labyrinth Diseases,Middle Aged,Neural Pathways,Nystagmus, Physiologic,Regression Analysis,Saccades,Vestibular Function Tests,Vestibule, Labyrinth,Journal Article},
  language     = {eng},
  month        = {05},
  number       = {5-6},
  pages        = {70--361},
  publisher    = {Taylor & Francis},
  series       = {Acta oto-laryngologica},
  title        = {The relationship of optokinetic nystagmus to pursuit eye movements, vestibular nystagmus and to saccades in humans. A clinical study},
  volume       = {101},
  year         = {1986},
}