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Information-to-work conversion in single-molecule experiments : From discrete to continuous feedback

Schmitt, Regina K. LU ; Potts, Patrick P. LU orcid ; Linke, Heiner LU orcid ; Johansson, Jonas LU orcid ; Samuelsson, Peter LU ; Rico-Pasto, Marc and Ritort, Felix (2023) In Physical Review E 107(5).
Abstract

We theoretically investigate the extractable work in single molecule unfolding-folding experiments with applied feedback. Using a simple two-state model, we obtain a description of the full work distribution from discrete to continuous feedback. The effect of the feedback is captured by a detailed fluctuation theorem, accounting for the information aquired. We find analytical expressions for the average work extraction as well as an experimentally measurable bound thereof, which becomes tight in the continuous feedback limit. We further determine the parameters for maximal power or rate of work extraction. Although our two-state model only depends on a single effective transition rate, we find qualitative agreement with Monte Carlo... (More)

We theoretically investigate the extractable work in single molecule unfolding-folding experiments with applied feedback. Using a simple two-state model, we obtain a description of the full work distribution from discrete to continuous feedback. The effect of the feedback is captured by a detailed fluctuation theorem, accounting for the information aquired. We find analytical expressions for the average work extraction as well as an experimentally measurable bound thereof, which becomes tight in the continuous feedback limit. We further determine the parameters for maximal power or rate of work extraction. Although our two-state model only depends on a single effective transition rate, we find qualitative agreement with Monte Carlo simulations of DNA hairpin unfolding-folding dynamics.

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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Review E
volume
107
issue
5
article number
L052104
publisher
American Physical Society
external identifiers
  • pmid:37329008
  • scopus:85163131602
ISSN
2470-0045
DOI
10.1103/PhysRevE.107.L052104
language
English
LU publication?
yes
id
e3a20222-743b-4f00-8a94-b0f138b5e4eb
date added to LUP
2023-09-22 14:22:39
date last changed
2024-04-19 01:33:29
@article{e3a20222-743b-4f00-8a94-b0f138b5e4eb,
  abstract     = {{<p>We theoretically investigate the extractable work in single molecule unfolding-folding experiments with applied feedback. Using a simple two-state model, we obtain a description of the full work distribution from discrete to continuous feedback. The effect of the feedback is captured by a detailed fluctuation theorem, accounting for the information aquired. We find analytical expressions for the average work extraction as well as an experimentally measurable bound thereof, which becomes tight in the continuous feedback limit. We further determine the parameters for maximal power or rate of work extraction. Although our two-state model only depends on a single effective transition rate, we find qualitative agreement with Monte Carlo simulations of DNA hairpin unfolding-folding dynamics.</p>}},
  author       = {{Schmitt, Regina K. and Potts, Patrick P. and Linke, Heiner and Johansson, Jonas and Samuelsson, Peter and Rico-Pasto, Marc and Ritort, Felix}},
  issn         = {{2470-0045}},
  language     = {{eng}},
  number       = {{5}},
  publisher    = {{American Physical Society}},
  series       = {{Physical Review E}},
  title        = {{Information-to-work conversion in single-molecule experiments : From discrete to continuous feedback}},
  url          = {{http://dx.doi.org/10.1103/PhysRevE.107.L052104}},
  doi          = {{10.1103/PhysRevE.107.L052104}},
  volume       = {{107}},
  year         = {{2023}},
}