Enzyme encapsulation in nanostructured self-assembled structures : Toward biofunctional supramolecular assemblies
(2019) In Current Opinion in Colloid and Interface Science 44. p.130-142- Abstract
Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting of polar lipid liquid crystals and hard ordered mesoporous silica matrices. For both types of matrices, the challenge is to control the pore size of the matrices and the interaction with the matrix interface. Here, the polar lipid liquid crystals offer larger flexibility than silica, but on the other hand, it is considerably more sensitive to... (More)
Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting of polar lipid liquid crystals and hard ordered mesoporous silica matrices. For both types of matrices, the challenge is to control the pore size of the matrices and the interaction with the matrix interface. Here, the polar lipid liquid crystals offer larger flexibility than silica, but on the other hand, it is considerably more sensitive to the environment.
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- author
- Valldeperas, Maria LU ; Salis, Andrea ; Barauskas, Justas LU ; Tiberg, Fredrik LU ; Arnebrant, Thomas ; Razumas, Valdemaras ; Monduzzi, Maura and Nylander, Tommy LU
- organization
- publishing date
- 2019-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cubic phase, Enzyme activity, Enzyme encapsulation, Mesoporous silica, Polar lipid liquid crystals, Pore size
- in
- Current Opinion in Colloid and Interface Science
- volume
- 44
- pages
- 13 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:85074691860
- ISSN
- 1359-0294
- DOI
- 10.1016/j.cocis.2019.09.007
- language
- English
- LU publication?
- yes
- id
- e7b72c85-4e7e-4c2e-9b0e-eee529e1a77c
- date added to LUP
- 2022-03-29 10:58:01
- date last changed
- 2023-11-12 21:10:46
@article{e7b72c85-4e7e-4c2e-9b0e-eee529e1a77c,
abstract = {{<p>Enzymes have come into use for many new applications outside their natural biological environment, taking advantage of their high efficiency and selectivity as biocatalysts. Such new application often requires encapsulation to preserve the structure and activity of the enzyme, but also to regulate and control the activity. Here, we will discuss two types of encapsulation, soft matrices consisting of polar lipid liquid crystals and hard ordered mesoporous silica matrices. For both types of matrices, the challenge is to control the pore size of the matrices and the interaction with the matrix interface. Here, the polar lipid liquid crystals offer larger flexibility than silica, but on the other hand, it is considerably more sensitive to the environment.</p>}},
author = {{Valldeperas, Maria and Salis, Andrea and Barauskas, Justas and Tiberg, Fredrik and Arnebrant, Thomas and Razumas, Valdemaras and Monduzzi, Maura and Nylander, Tommy}},
issn = {{1359-0294}},
keywords = {{Cubic phase; Enzyme activity; Enzyme encapsulation; Mesoporous silica; Polar lipid liquid crystals; Pore size}},
language = {{eng}},
pages = {{130--142}},
publisher = {{Elsevier}},
series = {{Current Opinion in Colloid and Interface Science}},
title = {{Enzyme encapsulation in nanostructured self-assembled structures : Toward biofunctional supramolecular assemblies}},
url = {{http://dx.doi.org/10.1016/j.cocis.2019.09.007}},
doi = {{10.1016/j.cocis.2019.09.007}},
volume = {{44}},
year = {{2019}},
}