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High HbA1c Levels Are Associated With Development of Trigger Finger in Type 1 and Type 2 Diabetes : An Observational Register-Based Study From Sweden

Rydberg, Mattias LU orcid ; Zimmerman, Malin LU orcid ; Gottsäter, Anders LU ; Eeg-Olofsson, Katarina and Dahlin, Lars B LU orcid (2022) In Diabetes Care 45(11). p.2669-2674
Abstract

OBJECTIVE: Trigger finger (TF) is a hand disorder causing the fingers to painfully lock in flexion. Diabetes is a known risk factor; however, whether strict glycemic control effectively lowers risk of TF is unknown. Our aim was to examine whether high HbA1c was associated with increased risk of TF among individuals with diabetes.

RESEARCH DESIGN AND METHODS: The Swedish National Diabetes Register (NDR) was cross-linked with the health care register of the Region of Skåne in southern Sweden. In total, 9,682 individuals with type 1 diabetes (T1D) and 85,755 individuals with type 2 diabetes (T2D) aged ≥18 years were included from 2004 to 2019. Associations between HbA1c and TF were calculated with sex-stratified, multivariate... (More)

OBJECTIVE: Trigger finger (TF) is a hand disorder causing the fingers to painfully lock in flexion. Diabetes is a known risk factor; however, whether strict glycemic control effectively lowers risk of TF is unknown. Our aim was to examine whether high HbA1c was associated with increased risk of TF among individuals with diabetes.

RESEARCH DESIGN AND METHODS: The Swedish National Diabetes Register (NDR) was cross-linked with the health care register of the Region of Skåne in southern Sweden. In total, 9,682 individuals with type 1 diabetes (T1D) and 85,755 individuals with type 2 diabetes (T2D) aged ≥18 years were included from 2004 to 2019. Associations between HbA1c and TF were calculated with sex-stratified, multivariate logistic regression models with 95% CIs, with adjustment for age, duration of diabetes, BMI, and systolic blood pressure.

RESULTS: In total, 486 women and 271 men with T1D and 1,143 women and 1,009 men with T2D were diagnosed with TF. Increased levels of HbA1c were associated with TF among individuals with T1D (women OR 1.26 [95% CI 1.1-1.4], P = 0.001, and men 1.4 [1.2-1.7], P < 0.001) and T2D (women 1.14 [95% CI 1.2-1.2], P < 0.001, and men 1.12 [95% CI 1.0-1.2], P = 0.003).

CONCLUSIONS: Hyperglycemia increases the risk of developing TF among individuals with T1D and T2D. Optimal treatment of diabetes seems to be of importance for prevention of diabetic hand complications such as TF.

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Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diabetes Care
volume
45
issue
11
pages
6 pages
publisher
American Diabetes Association
external identifiers
  • pmid:36006612
  • scopus:85141411718
ISSN
1935-5548
DOI
10.2337/dc22-0829
language
English
LU publication?
yes
additional info
© 2022 by the American Diabetes Association.
id
ea0c33a2-1cee-41df-b57a-26a28189d953
date added to LUP
2022-10-13 15:22:24
date last changed
2024-06-13 02:31:02
@article{ea0c33a2-1cee-41df-b57a-26a28189d953,
  abstract     = {{<p>OBJECTIVE: Trigger finger (TF) is a hand disorder causing the fingers to painfully lock in flexion. Diabetes is a known risk factor; however, whether strict glycemic control effectively lowers risk of TF is unknown. Our aim was to examine whether high HbA1c was associated with increased risk of TF among individuals with diabetes.</p><p>RESEARCH DESIGN AND METHODS: The Swedish National Diabetes Register (NDR) was cross-linked with the health care register of the Region of Skåne in southern Sweden. In total, 9,682 individuals with type 1 diabetes (T1D) and 85,755 individuals with type 2 diabetes (T2D) aged ≥18 years were included from 2004 to 2019. Associations between HbA1c and TF were calculated with sex-stratified, multivariate logistic regression models with 95% CIs, with adjustment for age, duration of diabetes, BMI, and systolic blood pressure.</p><p>RESULTS: In total, 486 women and 271 men with T1D and 1,143 women and 1,009 men with T2D were diagnosed with TF. Increased levels of HbA1c were associated with TF among individuals with T1D (women OR 1.26 [95% CI 1.1-1.4], P = 0.001, and men 1.4 [1.2-1.7], P &lt; 0.001) and T2D (women 1.14 [95% CI 1.2-1.2], P &lt; 0.001, and men 1.12 [95% CI 1.0-1.2], P = 0.003).</p><p>CONCLUSIONS: Hyperglycemia increases the risk of developing TF among individuals with T1D and T2D. Optimal treatment of diabetes seems to be of importance for prevention of diabetic hand complications such as TF.</p>}},
  author       = {{Rydberg, Mattias and Zimmerman, Malin and Gottsäter, Anders and Eeg-Olofsson, Katarina and Dahlin, Lars B}},
  issn         = {{1935-5548}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{2669--2674}},
  publisher    = {{American Diabetes Association}},
  series       = {{Diabetes Care}},
  title        = {{High HbA1c Levels Are Associated With Development of Trigger Finger in Type 1 and Type 2 Diabetes : An Observational Register-Based Study From Sweden}},
  url          = {{http://dx.doi.org/10.2337/dc22-0829}},
  doi          = {{10.2337/dc22-0829}},
  volume       = {{45}},
  year         = {{2022}},
}