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Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

Olsson, A ; Hellgren, M ; Berntorp, Erik LU and Baghaei, F (2015) In Haemophilia 21(6). p.742-746
Abstract
Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Haemophilia
volume
21
issue
6
pages
742 - 746
publisher
Wiley-Blackwell
external identifiers
  • pmid:26346645
  • wos:000363508900148
  • scopus:84946495640
  • pmid:26346645
ISSN
1351-8216
DOI
10.1111/hae.12796
language
English
LU publication?
yes
id
eb0a4ec6-6576-4d6a-ae15-262b2eaf9e1a (old id 8042921)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26346645?dopt=Abstract
date added to LUP
2016-04-01 10:27:51
date last changed
2022-07-21 17:47:35
@article{eb0a4ec6-6576-4d6a-ae15-262b2eaf9e1a,
  abstract     = {{Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).}},
  author       = {{Olsson, A and Hellgren, M and Berntorp, Erik and Baghaei, F}},
  issn         = {{1351-8216}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{742--746}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Haemophilia}},
  title        = {{Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.}},
  url          = {{http://dx.doi.org/10.1111/hae.12796}},
  doi          = {{10.1111/hae.12796}},
  volume       = {{21}},
  year         = {{2015}},
}