Reciprocal translocation (11;19)(q23;p13) in congenital acute lymphoblastic leukemia
Heim, Sverre LU ; Kristoffersson, Ulf LU ; Mandahl, Nils LU ; Mitelman, Felix LU
; Békássy, Albert
LU
; Garwicz, Stanislaw
LU
; Heldrup, Jesper
LU
and Wiebe, Thomas
LU
(1986)
In Cancer Genetics and Cytogenetics
23(3).
p.239-244
- Abstract
- The cytogenetic, clinical, and immunologic findings ina 4-month-old girl with acute lymphoblastic leukemia (ALL) are reported. The malignant lymphoblasts were characterized cytogenetically by the reciprocal translocation t(11;19)(q23;p13); immunologically by an immature pre-B-ALL phenotype. In spite of the high-risk nature of the leukemia, the patient attained complete remission relatively quickly and is still free of disease 3 years after diagnosis. Because the only two previously reported ALL patients with t(11;19) also seem to have responded well to therapy, this cytogenetic abnormality might turn out to be an indicator of favorable prognosis in ALL.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1103513
- author
- Heim, Sverre
LU
; Kristoffersson, Ulf
LU
; Mandahl, Nils
LU
; Mitelman, Felix
LU
; Békássy, Albert
LU
; Garwicz, Stanislaw
LU
; Heldrup, Jesper
LU
and Wiebe, Thomas
LU
- organization
- publishing date
- 1986
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cancer Genetics and Cytogenetics
- volume
- 23
- issue
- 3
- pages
- 239 - 244
- publisher
- Elsevier
- external identifiers
-
- pmid:3464343
- scopus:0023009892
- ISSN
- 0165-4608
- DOI
- 10.1016/0165-4608(86)90183-4
- language
- English
- LU publication?
- yes
- id
- efb404cf-0676-41a0-9947-7466dabcdd72 (old id 1103513)
- date added to LUP
- 2016-04-01 16:37:09
- date last changed
- 2021-01-03 05:30:38
@article{efb404cf-0676-41a0-9947-7466dabcdd72,
abstract = {{The cytogenetic, clinical, and immunologic findings ina 4-month-old girl with acute lymphoblastic leukemia (ALL) are reported. The malignant lymphoblasts were characterized cytogenetically by the reciprocal translocation t(11;19)(q23;p13); immunologically by an immature pre-B-ALL phenotype. In spite of the high-risk nature of the leukemia, the patient attained complete remission relatively quickly and is still free of disease 3 years after diagnosis. Because the only two previously reported ALL patients with t(11;19) also seem to have responded well to therapy, this cytogenetic abnormality might turn out to be an indicator of favorable prognosis in ALL.}},
author = {{Heim, Sverre and Kristoffersson, Ulf and Mandahl, Nils and Mitelman, Felix and Békássy, Albert and Garwicz, Stanislaw and Heldrup, Jesper and Wiebe, Thomas}},
issn = {{0165-4608}},
language = {{eng}},
number = {{3}},
pages = {{239--244}},
publisher = {{Elsevier}},
series = {{Cancer Genetics and Cytogenetics}},
title = {{Reciprocal translocation (11;19)(q23;p13) in congenital acute lymphoblastic leukemia}},
url = {{http://dx.doi.org/10.1016/0165-4608(86)90183-4}},
doi = {{10.1016/0165-4608(86)90183-4}},
volume = {{23}},
year = {{1986}},
}