Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways

Tas, Sinem LU ; Rehnberg, Emil LU and Wagner, Darcy E. LU orcid (2022) p.171-195
Abstract

Recent advances in materials science coupled with advanced manufacturing techniques have opened up new possibilities for generating sophisticated models of lung and airways containing cells. These models can be used for studying normal tissue homeostasis as well as for modeling lung development, disease, and regeneration. Three-dimensional (3D) printing has emerged as a leading advanced manufacturing technique for generating models as well as producing clinically relevant constructs. In fact, 3D-printed, cell-free support structures have already been used clinically in a few case reports for airways. While 3D bioprinting is poised to play a major role in both preclinical and clinical science, only a few constructs containing cells have... (More)

Recent advances in materials science coupled with advanced manufacturing techniques have opened up new possibilities for generating sophisticated models of lung and airways containing cells. These models can be used for studying normal tissue homeostasis as well as for modeling lung development, disease, and regeneration. Three-dimensional (3D) printing has emerged as a leading advanced manufacturing technique for generating models as well as producing clinically relevant constructs. In fact, 3D-printed, cell-free support structures have already been used clinically in a few case reports for airways. While 3D bioprinting is poised to play a major role in both preclinical and clinical science, only a few constructs containing cells have been made to date. Preclinical models of 3D-bioprinted tracheas containing cells show promise, but there is a paucity of reports for distal lung, owing to a lack of bioinks. This chapter discusses the use of advanced manufacturing to bioengineer 3D constructs for lung and airways.

(Less)
Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
additive manufacturing, bioengineering, lung bioengineering, Materials synthesis, tissue engineering
host publication
3D Lung Models for Regenerating Lung Tissue
editor
Westergren-Thorsson, G and Rolandsson Enes, S
pages
171 - 195
publisher
ScienceDirect, Elsevier
external identifiers
  • scopus:85142787119
ISBN
9780323908726
9780323908719
DOI
10.1016/B978-0-323-90871-9.00003-6
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2022 Elsevier Inc. All rights reserved.
id
f42d7ce6-1585-4e5f-afb4-b1f0c557d85e
date added to LUP
2022-12-10 22:35:20
date last changed
2024-04-04 08:23:30
@inbook{f42d7ce6-1585-4e5f-afb4-b1f0c557d85e,
  abstract     = {{<p>Recent advances in materials science coupled with advanced manufacturing techniques have opened up new possibilities for generating sophisticated models of lung and airways containing cells. These models can be used for studying normal tissue homeostasis as well as for modeling lung development, disease, and regeneration. Three-dimensional (3D) printing has emerged as a leading advanced manufacturing technique for generating models as well as producing clinically relevant constructs. In fact, 3D-printed, cell-free support structures have already been used clinically in a few case reports for airways. While 3D bioprinting is poised to play a major role in both preclinical and clinical science, only a few constructs containing cells have been made to date. Preclinical models of 3D-bioprinted tracheas containing cells show promise, but there is a paucity of reports for distal lung, owing to a lack of bioinks. This chapter discusses the use of advanced manufacturing to bioengineer 3D constructs for lung and airways.</p>}},
  author       = {{Tas, Sinem and Rehnberg, Emil and Wagner, Darcy E.}},
  booktitle    = {{3D Lung Models for Regenerating Lung Tissue}},
  editor       = {{Westergren-Thorsson, G and Rolandsson Enes, S}},
  isbn         = {{9780323908726}},
  keywords     = {{additive manufacturing; bioengineering; lung bioengineering; Materials synthesis; tissue engineering}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{171--195}},
  publisher    = {{ScienceDirect, Elsevier}},
  title        = {{Advanced manufacturing: three-dimensional printing and bioprinting of models of lung and airways}},
  url          = {{http://dx.doi.org/10.1016/B978-0-323-90871-9.00003-6}},
  doi          = {{10.1016/B978-0-323-90871-9.00003-6}},
  year         = {{2022}},
}