Research gaps and opportunities in precision nutrition : an NIH workshop report
(2022) In The American journal of clinical nutrition 116(6). p.1877-1900- Abstract
Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health status, behaviors, social influences, and environmental exposures. On 11-12 January 2021, the National Institutes of Health convened a workshop entitled "Precision Nutrition: Research Gaps and Opportunities" to bring together experts to discuss the issues involved in better understanding and addressing precision nutrition. The workshop proceeded... (More)
Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health status, behaviors, social influences, and environmental exposures. On 11-12 January 2021, the National Institutes of Health convened a workshop entitled "Precision Nutrition: Research Gaps and Opportunities" to bring together experts to discuss the issues involved in better understanding and addressing precision nutrition. The workshop proceeded in 3 parts: part I covered many aspects of genetics and physiology that mediate the links between nutrient intake and health conditions such as cardiovascular disease, Alzheimer disease, and cancer; part II reviewed potential contributors to interindividual variability in dietary exposures and responses such as baseline nutritional status, circadian rhythm/sleep, environmental exposures, sensory properties of food, stress, inflammation, and the social determinants of health; part III presented the need for systems approaches, with new methods and technologies that can facilitate the study and implementation of precision nutrition, and workforce development needed to create a new generation of researchers. The workshop concluded that much research will be needed before more precise nutrition recommendations can be achieved. This includes better understanding and accounting for variables such as age, sex, ethnicity, medical history, genetics, and social and environmental factors. The advent of new methods and technologies and the availability of considerably more data bring tremendous opportunity. However, the field must proceed with appropriate levels of caution and make sure the factors listed above are all considered, and systems approaches and methods are incorporated. It will be important to develop and train an expanded workforce with the goal of reducing health disparities and improving precision nutritional advice for all Americans.
(Less)
- author
- organization
- publishing date
- 2022-12-19
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- data science, food, genomics, nutrigenomics, precision nutrition
- in
- The American journal of clinical nutrition
- volume
- 116
- issue
- 6
- pages
- 24 pages
- publisher
- Oxford University Press
- external identifiers
-
- pmid:36055772
- scopus:85144590054
- ISSN
- 1938-3207
- DOI
- 10.1093/ajcn/nqac237
- language
- English
- LU publication?
- yes
- id
- f842a286-ca69-4eec-b161-9e1e5a6b87b8
- date added to LUP
- 2023-01-05 13:06:58
- date last changed
- 2024-04-18 17:43:11
@article{f842a286-ca69-4eec-b161-9e1e5a6b87b8,
abstract = {{<p>Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health status, behaviors, social influences, and environmental exposures. On 11-12 January 2021, the National Institutes of Health convened a workshop entitled "Precision Nutrition: Research Gaps and Opportunities" to bring together experts to discuss the issues involved in better understanding and addressing precision nutrition. The workshop proceeded in 3 parts: part I covered many aspects of genetics and physiology that mediate the links between nutrient intake and health conditions such as cardiovascular disease, Alzheimer disease, and cancer; part II reviewed potential contributors to interindividual variability in dietary exposures and responses such as baseline nutritional status, circadian rhythm/sleep, environmental exposures, sensory properties of food, stress, inflammation, and the social determinants of health; part III presented the need for systems approaches, with new methods and technologies that can facilitate the study and implementation of precision nutrition, and workforce development needed to create a new generation of researchers. The workshop concluded that much research will be needed before more precise nutrition recommendations can be achieved. This includes better understanding and accounting for variables such as age, sex, ethnicity, medical history, genetics, and social and environmental factors. The advent of new methods and technologies and the availability of considerably more data bring tremendous opportunity. However, the field must proceed with appropriate levels of caution and make sure the factors listed above are all considered, and systems approaches and methods are incorporated. It will be important to develop and train an expanded workforce with the goal of reducing health disparities and improving precision nutritional advice for all Americans.</p>}},
author = {{Lee, Bruce Y. and Ordovás, José M. and Parks, Elizabeth J. and Anderson, Cheryl A.M. and Barabási, Albert László and Clinton, Steven K. and de la Haye, Kayla and Duffy, Valerie B. and Franks, Paul W. and Ginexi, Elizabeth M. and Hammond, Kristian J. and Hanlon, Erin C. and Hittle, Michael and Ho, Emily and Horn, Abigail L. and Isaacson, Richard S. and Mabry, Patricia L. and Malone, Susan and Martin, Corby K. and Mattei, Josiemer and Meydani, Simin Nikbin and Nelson, Lorene M. and Neuhouser, Marian L. and Parent, Brendan and Pronk, Nicolaas P. and Roche, Helen M. and Saria, Suchi and Scheer, Frank A.J.L. and Segal, Eran and Sevick, Mary Ann and Spector, Tim D. and Van Horn, Linda and Varady, Krista A. and Voruganti, Venkata Saroja and Martinez, Marie F.}},
issn = {{1938-3207}},
keywords = {{data science; food; genomics; nutrigenomics; precision nutrition}},
language = {{eng}},
month = {{12}},
number = {{6}},
pages = {{1877--1900}},
publisher = {{Oxford University Press}},
series = {{The American journal of clinical nutrition}},
title = {{Research gaps and opportunities in precision nutrition : an NIH workshop report}},
url = {{http://dx.doi.org/10.1093/ajcn/nqac237}},
doi = {{10.1093/ajcn/nqac237}},
volume = {{116}},
year = {{2022}},
}