Advanced

Porous silicon immunoaffinity microarrays

Adler, Belinda LU ; Yan, Hong LU ; Ekström, Simon LU and Laurell, Thomas LU (2018) 2-2. p.1355-1367
Abstract

Porous silicon with immobilized recognition biomolecules is an attractive platform for many microfluidic chip-based bioanalytical applications. We review the progress in the field since its earliest developments in the 1990s. An improved assay for early detection of prostate cancer has reached clinical evaluation, but there are also exciting developments in both aptamer-based biosensing and mass spectrometry-based biosensing.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Cassie Baxter mode, Desorption/ionization on silicon (DIOS), Fluorescence quenching assay, Immunocapture and MALDI (iMALDI MS), Prostate specific antigen (PSA), Sol-gel aptamer microarrays, Solid/fluid interaction
host publication
Handbook of Porous Silicon
editor
Canham, Leigh and
volume
2-2
pages
13 pages
publisher
Springer International Publishing AG
external identifiers
  • scopus:85053980640
ISBN
9783319713816
9783319713793
DOI
10.1007/978-3-319-71381-6_89
language
English
LU publication?
yes
id
f882ec3f-6b32-4d5f-9d2e-edea6c1aeaec
date added to LUP
2018-10-18 14:29:45
date last changed
2019-02-20 11:32:00
@inbook{f882ec3f-6b32-4d5f-9d2e-edea6c1aeaec,
  abstract     = {<p>Porous silicon with immobilized recognition biomolecules is an attractive platform for many microfluidic chip-based bioanalytical applications. We review the progress in the field since its earliest developments in the 1990s. An improved assay for early detection of prostate cancer has reached clinical evaluation, but there are also exciting developments in both aptamer-based biosensing and mass spectrometry-based biosensing.</p>},
  author       = {Adler, Belinda and Yan, Hong and Ekström, Simon and Laurell, Thomas},
  editor       = {Canham, Leigh },
  isbn         = {9783319713816},
  keyword      = {Cassie Baxter mode,Desorption/ionization on silicon (DIOS),Fluorescence quenching assay,Immunocapture and MALDI (iMALDI MS),Prostate specific antigen (PSA),Sol-gel aptamer microarrays,Solid/fluid interaction},
  language     = {eng},
  pages        = {1355--1367},
  publisher    = {Springer International Publishing AG},
  title        = {Porous silicon immunoaffinity microarrays},
  url          = {http://dx.doi.org/10.1007/978-3-319-71381-6_89},
  volume       = {2-2},
  year         = {2018},
}