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HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

Ivarsson, S ‐A LU ; ERIKSSON, S. ; KOCKUM, I. ; LERNMARK, Å LU ; LINDGREN, S. ; NILSSON, K. O. LU ; SUNDKVIST, G. LU and WASSMUTH, R. (1993) In Journal of Internal Medicine 233(3). p.281-286
Abstract

Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd

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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diabetes mellitus type I, sclerosing cholangitis, ulcerative colitis
in
Journal of Internal Medicine
volume
233
issue
3
pages
281 - 286
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • scopus:0027415112
  • pmid:8450297
ISSN
0954-6820
DOI
10.1111/j.1365-2796.1993.tb00988.x
language
English
LU publication?
yes
id
f9d6c49a-4310-4048-b943-1d834428c0cf
date added to LUP
2019-09-11 09:27:16
date last changed
2020-04-07 10:29:28
@article{f9d6c49a-4310-4048-b943-1d834428c0cf,
  abstract     = {<p>Abstract.  Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd</p>},
  author       = {Ivarsson, S ‐A and ERIKSSON, S. and KOCKUM, I. and LERNMARK, Å and LINDGREN, S. and NILSSON, K. O. and SUNDKVIST, G. and WASSMUTH, R.},
  issn         = {0954-6820},
  language     = {eng},
  month        = {01},
  number       = {3},
  pages        = {281--286},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Journal of Internal Medicine},
  title        = {HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis},
  url          = {http://dx.doi.org/10.1111/j.1365-2796.1993.tb00988.x},
  doi          = {10.1111/j.1365-2796.1993.tb00988.x},
  volume       = {233},
  year         = {1993},
}