Self-gated fetal cardiac MRI with tiny golden angle iGRASP : A feasibility study
(2017) In Journal of Magnetic Resonance Imaging 46(1). p.207-217- Abstract
PURPOSE: To develop and assess a technique for self-gated fetal cardiac cine magnetic resonance imaging (MRI) using tiny golden angle radial sampling combined with iGRASP (iterative Golden-angle RAdial Sparse Parallel) for accelerated acquisition based on parallel imaging and compressed sensing.
MATERIALS AND METHODS: Fetal cardiac data were acquired from five volunteers in gestational week 29-37 at 1.5T using tiny golden angles for eddy currents reduction. The acquired multicoil radial projections were input to a principal component analysis-based compression stage. The cardiac self-gating (CSG) signal for cardiac gating was extracted from the acquired radial projections and the iGRASP reconstruction procedure was applied. In all... (More)
PURPOSE: To develop and assess a technique for self-gated fetal cardiac cine magnetic resonance imaging (MRI) using tiny golden angle radial sampling combined with iGRASP (iterative Golden-angle RAdial Sparse Parallel) for accelerated acquisition based on parallel imaging and compressed sensing.
MATERIALS AND METHODS: Fetal cardiac data were acquired from five volunteers in gestational week 29-37 at 1.5T using tiny golden angles for eddy currents reduction. The acquired multicoil radial projections were input to a principal component analysis-based compression stage. The cardiac self-gating (CSG) signal for cardiac gating was extracted from the acquired radial projections and the iGRASP reconstruction procedure was applied. In all acquisitions, a total of 4000 radial spokes were acquired within a breath-hold of less than 15 seconds using a balanced steady-state free precession pulse sequence. The images were qualitatively compared by two independent observers (on a scale of 1-4) to a single midventricular cine image from metric optimized gating (MOG) and real-time acquisitions.
RESULTS: For iGRASP and MOG images, good overall image quality (2.8 ± 0.4 and 2.6 ± 1.3, respectively, for observer 1; 3.6 ± 0.5 and 3.4 ± 0.9, respectively, for observer 2) and cardiac diagnostic quality (3.8 ± 0.4 and 3.4 ± 0.9, respectively, for observer 1; 3.6 ± 0.5 and 3.6 ± 0.9, respectively, for observer 2) were obtained, with visualized myocardial thickening over the cardiac cycle and well-defined myocardial borders to ventricular lumen and liver/lung tissue. For iGRASP, MOG, and real time, left ventricular lumen diameter (14.1 ± 2.2 mm, 14.2 ± 1.9 mm, 14.7 ± 1.1 mm, respectively) and wall thickness (2.7 ± 0.3 mm, 2.6 ± 0.3 mm, 3.0 ± 0.4, respectively) showed agreement and no statistically significant difference was found (all P > 0.05). Images with iGRASP tended to have higher overall image quality scores compared with MOG and particularly real-time images, albeit not statistically significant in this feasibility study (P > 0.99 and P = 0.12, respectively).
CONCLUSION: Fetal cardiac cine MRI can be performed with iGRASP using tiny golden angles and CSG. Comparison with other fetal cardiac cine MRI methods showed that the proposed method produces high-quality fetal cardiac reconstructions.
LEVEL OF EVIDENCE: 2 J. Magn. Reson. Imaging 2017.
(Less)
- author
- Haris, Kostas
LU
; Hedström, Erik
LU
; Bidhult, Sebastian LU ; Testud, Frederik LU
; Maglaveras, Nicos ; Heiberg, Einar LU ; Hansson, Stefan LU
; Arheden, Håkan LU and Aletras, Anthony H LU
- organization
- publishing date
- 2017-07
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Journal Article
- in
- Journal of Magnetic Resonance Imaging
- volume
- 46
- issue
- 1
- pages
- 207 - 217
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85011649957
- wos:000403006100020
- pmid:28152243
- ISSN
- 1522-2586
- DOI
- 10.1002/jmri.25599
- language
- English
- LU publication?
- yes
- id
- faaf84c2-27a1-4a3c-bbcb-6298928e227c
- date added to LUP
- 2017-03-06 21:29:43
- date last changed
- 2025-02-03 11:48:36
@article{faaf84c2-27a1-4a3c-bbcb-6298928e227c, abstract = {{<p>PURPOSE: To develop and assess a technique for self-gated fetal cardiac cine magnetic resonance imaging (MRI) using tiny golden angle radial sampling combined with iGRASP (iterative Golden-angle RAdial Sparse Parallel) for accelerated acquisition based on parallel imaging and compressed sensing.</p><p>MATERIALS AND METHODS: Fetal cardiac data were acquired from five volunteers in gestational week 29-37 at 1.5T using tiny golden angles for eddy currents reduction. The acquired multicoil radial projections were input to a principal component analysis-based compression stage. The cardiac self-gating (CSG) signal for cardiac gating was extracted from the acquired radial projections and the iGRASP reconstruction procedure was applied. In all acquisitions, a total of 4000 radial spokes were acquired within a breath-hold of less than 15 seconds using a balanced steady-state free precession pulse sequence. The images were qualitatively compared by two independent observers (on a scale of 1-4) to a single midventricular cine image from metric optimized gating (MOG) and real-time acquisitions.</p><p>RESULTS: For iGRASP and MOG images, good overall image quality (2.8 ± 0.4 and 2.6 ± 1.3, respectively, for observer 1; 3.6 ± 0.5 and 3.4 ± 0.9, respectively, for observer 2) and cardiac diagnostic quality (3.8 ± 0.4 and 3.4 ± 0.9, respectively, for observer 1; 3.6 ± 0.5 and 3.6 ± 0.9, respectively, for observer 2) were obtained, with visualized myocardial thickening over the cardiac cycle and well-defined myocardial borders to ventricular lumen and liver/lung tissue. For iGRASP, MOG, and real time, left ventricular lumen diameter (14.1 ± 2.2 mm, 14.2 ± 1.9 mm, 14.7 ± 1.1 mm, respectively) and wall thickness (2.7 ± 0.3 mm, 2.6 ± 0.3 mm, 3.0 ± 0.4, respectively) showed agreement and no statistically significant difference was found (all P > 0.05). Images with iGRASP tended to have higher overall image quality scores compared with MOG and particularly real-time images, albeit not statistically significant in this feasibility study (P > 0.99 and P = 0.12, respectively).</p><p>CONCLUSION: Fetal cardiac cine MRI can be performed with iGRASP using tiny golden angles and CSG. Comparison with other fetal cardiac cine MRI methods showed that the proposed method produces high-quality fetal cardiac reconstructions.</p><p>LEVEL OF EVIDENCE: 2 J. Magn. Reson. Imaging 2017.</p>}}, author = {{Haris, Kostas and Hedström, Erik and Bidhult, Sebastian and Testud, Frederik and Maglaveras, Nicos and Heiberg, Einar and Hansson, Stefan and Arheden, Håkan and Aletras, Anthony H}}, issn = {{1522-2586}}, keywords = {{Journal Article}}, language = {{eng}}, number = {{1}}, pages = {{207--217}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Journal of Magnetic Resonance Imaging}}, title = {{Self-gated fetal cardiac MRI with tiny golden angle iGRASP : A feasibility study}}, url = {{http://dx.doi.org/10.1002/jmri.25599}}, doi = {{10.1002/jmri.25599}}, volume = {{46}}, year = {{2017}}, }