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Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design

Jones, Charles H; Hakansson, Anders P LU and Pfeifer, Blaine A (2014) In Journal of Materials Chemistry. B 46. p.8053-8068
Abstract

The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.

Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
in
Journal of Materials Chemistry. B
volume
46
pages
8053 - 8068
publisher
Royal Society of Chemistry
external identifiers
  • scopus:84908577903
ISSN
2050-750X
DOI
10.1039/C4TB01058B
language
English
LU publication?
no
id
fc6af738-3c1d-4b12-b812-5e58cfcaa04f
date added to LUP
2018-09-21 13:37:19
date last changed
2018-09-24 08:53:22
@article{fc6af738-3c1d-4b12-b812-5e58cfcaa04f,
  abstract     = {<p>The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.</p>},
  author       = {Jones, Charles H and Hakansson, Anders P and Pfeifer, Blaine A},
  issn         = {2050-750X},
  language     = {eng},
  pages        = {8053--8068},
  publisher    = {Royal Society of Chemistry},
  series       = {Journal of Materials Chemistry. B},
  title        = {Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design},
  url          = {http://dx.doi.org/10.1039/C4TB01058B},
  volume       = {46},
  year         = {2014},
}