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NG2 cells, a new trail for Alzheimer's disease mechanisms?

Nielsen, Henrietta LU ; Ek, Danyal LU ; Avdic, Una ; Orbjörn, Camilla LU ; Hansson, Oskar LU orcid ; Veerhuis, Robert ; Rozemuller, Annemieke Jm ; Brun, Arne LU ; Minthon, Lennart LU and Wennström, Malin LU (2013) In Acta Neuropathologica Communications 1(1).
Abstract
Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Neuropathologica Communications
volume
1
issue
1
article number
7
publisher
BioMed Central (BMC)
external identifiers
  • pmid:24252600
  • pmid:24252600
  • scopus:85005808157
ISSN
2051-5960
DOI
10.1186/2051-5960-1-7
language
English
LU publication?
yes
id
fe2597a0-e956-47e2-9d3b-044691dc5c49 (old id 4179178)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24252600?dopt=Abstract
date added to LUP
2016-04-01 14:09:38
date last changed
2022-05-15 17:06:00
@article{fe2597a0-e956-47e2-9d3b-044691dc5c49,
  abstract     = {{Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).}},
  author       = {{Nielsen, Henrietta and Ek, Danyal and Avdic, Una and Orbjörn, Camilla and Hansson, Oskar and Veerhuis, Robert and Rozemuller, Annemieke Jm and Brun, Arne and Minthon, Lennart and Wennström, Malin}},
  issn         = {{2051-5960}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Acta Neuropathologica Communications}},
  title        = {{NG2 cells, a new trail for Alzheimer's disease mechanisms?}},
  url          = {{https://lup.lub.lu.se/search/files/3820151/4431951.pdf}},
  doi          = {{10.1186/2051-5960-1-7}},
  volume       = {{1}},
  year         = {{2013}},
}