NG2 cells, a new trail for Alzheimer's disease mechanisms?
(2013) In Acta Neuropathologica Communications 1(1).- Abstract
- Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4179178
- author
- Nielsen, Henrietta LU ; Ek, Danyal LU ; Avdic, Una ; Orbjörn, Camilla LU ; Hansson, Oskar LU ; Veerhuis, Robert ; Rozemuller, Annemieke Jm ; Brun, Arne LU ; Minthon, Lennart LU and Wennström, Malin LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Neuropathologica Communications
- volume
- 1
- issue
- 1
- article number
- 7
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:24252600
- pmid:24252600
- scopus:85005808157
- ISSN
- 2051-5960
- DOI
- 10.1186/2051-5960-1-7
- language
- English
- LU publication?
- yes
- id
- fe2597a0-e956-47e2-9d3b-044691dc5c49 (old id 4179178)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24252600?dopt=Abstract
- date added to LUP
- 2016-04-01 14:09:38
- date last changed
- 2022-05-15 17:06:00
@article{fe2597a0-e956-47e2-9d3b-044691dc5c49, abstract = {{Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).}}, author = {{Nielsen, Henrietta and Ek, Danyal and Avdic, Una and Orbjörn, Camilla and Hansson, Oskar and Veerhuis, Robert and Rozemuller, Annemieke Jm and Brun, Arne and Minthon, Lennart and Wennström, Malin}}, issn = {{2051-5960}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{Acta Neuropathologica Communications}}, title = {{NG2 cells, a new trail for Alzheimer's disease mechanisms?}}, url = {{https://lup.lub.lu.se/search/files/3820151/4431951.pdf}}, doi = {{10.1186/2051-5960-1-7}}, volume = {{1}}, year = {{2013}}, }