Excess mortality in middle-aged men with diabetes aged 15-34 years at diagnosis.
(2011) In Acta Diabetologica 48. p.197-202- Abstract
- The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5).... (More)
- The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5). Diabetes as the underlying cause of death accounted for 38% (11/29) of deaths among patients. Most patients, 55% (16/29), died at home, remaining patients in hospital, 28% (8/29), or elsewhere 17% (5/29) compared to controls of whom 33% (3/9; P = 0.45) died at home, 33% (3/9; P = 1.0) in hospital, and 33% (3/9; P = 0.36) elsewhere. Only 55% (16/29) of patients had a specified day of death on death certificates compared to 100% (9/9; P = 0.016) of controls. Adult men with diabetes had an almost threefold increased risk to die within 15 years of diagnosis compared to healthy men. Most middle-aged patients with diabetes died at home and often without a specified date of death recorded. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1884126
- author
- Törn, Carina LU ; Ingemansson, Sofie LU ; Lindblad, Ulf LU and Gudbjörnsdottir, Soffia
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Acta Diabetologica
- volume
- 48
- pages
- 197 - 202
- publisher
- Springer
- external identifiers
-
- wos:000294344600004
- pmid:21390553
- scopus:80052361682
- ISSN
- 1432-5233
- DOI
- 10.1007/s00592-011-0272-2
- language
- English
- LU publication?
- yes
- id
- ff5b3da5-6e7e-4f11-9053-93da864bcb4e (old id 1884126)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21390553?dopt=Abstract
- date added to LUP
- 2016-04-04 09:36:16
- date last changed
- 2022-01-29 18:38:00
@article{ff5b3da5-6e7e-4f11-9053-93da864bcb4e, abstract = {{The aim of this study is to assess mortality risk and the excess of risk in patients with diabetes. Patients were 15-34 years old at diagnosis of diabetes mellitus (n = 879) in 1992 and 1993 in this national cohort from Sweden. Healthy controls were matched for gender and birth on the same day as the index cases (n = 837). The civic registration number was used to link patients and controls to the Swedish Cause of Death Registry. During follow-up, 3.3% (29/879) of patients and 1.1% (9/837; P = 0.002) of controls died. The risk for a patient with diabetes to die was almost threefold increased compared with healthy controls; hazard ratio, 2.9 (95% CI 1.4-6.2). This increased risk was significant in men; hazard ratio, 2.8 (95% CI 1.2-6.5). Diabetes as the underlying cause of death accounted for 38% (11/29) of deaths among patients. Most patients, 55% (16/29), died at home, remaining patients in hospital, 28% (8/29), or elsewhere 17% (5/29) compared to controls of whom 33% (3/9; P = 0.45) died at home, 33% (3/9; P = 1.0) in hospital, and 33% (3/9; P = 0.36) elsewhere. Only 55% (16/29) of patients had a specified day of death on death certificates compared to 100% (9/9; P = 0.016) of controls. Adult men with diabetes had an almost threefold increased risk to die within 15 years of diagnosis compared to healthy men. Most middle-aged patients with diabetes died at home and often without a specified date of death recorded.}}, author = {{Törn, Carina and Ingemansson, Sofie and Lindblad, Ulf and Gudbjörnsdottir, Soffia}}, issn = {{1432-5233}}, language = {{eng}}, pages = {{197--202}}, publisher = {{Springer}}, series = {{Acta Diabetologica}}, title = {{Excess mortality in middle-aged men with diabetes aged 15-34 years at diagnosis.}}, url = {{http://dx.doi.org/10.1007/s00592-011-0272-2}}, doi = {{10.1007/s00592-011-0272-2}}, volume = {{48}}, year = {{2011}}, }