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- 2022
-
Mark
Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease
Zetterberg, Fredrik R. ; Mackinnon, Alison ; Brimert, Thomas ; Gravelle, Lise ; Johnsson, Richard E. ; Kahl-Knutson, Barbro LU ; Leffler, Hakon LU ; Nilsson, Ulf J. LU
; Pedersen, Anders
and Peterson, Kristoffer
LU
, et al.
(2022)
In Journal of Medicinal Chemistry
65(19).
p.12626-12638
- Contribution to journal › Article
-
Mark
Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia
Bum-Erdene, Khuchtumur ; Collins, Patrick M. ; Hugo, Matthew W. ; Tarighat, Somayeh S. ; Fei, Fei ; Kishor, Chandan ; Leffler, Hakon LU ; Nilsson, Ulf J. LU
; Groffen, John
and Grice, I. Darren
, et al.
(2022)
In Journal of Medicinal Chemistry
65(8).
p.5975-5989
- Contribution to journal › Article
-
Mark
Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors
van Klaveren, Sjors LU ; Dernovšek, Jaka ; Jakopin, Žiga ; Anderluh, Marko ; Leffler, Hakon LU ; Nilsson, Ulf J. LU
and Tomašič, Tihomir
(2022)
In RSC Advances
12(29).
p.18973-18984
- Contribution to journal › Article
-
Mark
Galectin-9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix
Pally, Dharma ; Banerjee, Mallar ; Hussain, Shahid ; Kumar, Rekha V ; Petersson, Alexandra LU ; Rosendal, Ebba ; Gunnarsson, Ludvig ; Peterson, Kristoffer LU ; Leffler, Hakon LU and Nilsson, Ulf J LU
, et al.
(2022)
In ACS Chemical Biology
17(6).
p.1376-1386
- Contribution to journal › Article
-
Mark
Site-specific N-glycan profiles of α5β1 integrin from rat liver
- Contribution to journal › Article
-
Mark
Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins
- Contribution to journal › Article
- 2021
-
Mark
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
Hirani, Nikhil ; MacKinnon, Alison C. ; Nicol, Lisa ; Ford, Paul ; Schambye, Hans ; Pedersen, Anders ; Nilsson, Ulf J. LU
; Leffler, Hakon
LU
; Sethi, Tariq
and Tantawi, Susan
, et al.
(2021)
In European Respiratory Journal
57(5).
- Contribution to journal › Article
-
Mark
Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation
- Contribution to journal › Article
-
Mark
Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C
Wallerstein, Johan LU
; Ekberg, Vilhelm
LU
; Misini Ignjatović, Majda
LU
; Kumar, Rohit
LU
; Caldararu, Octav
LU
; Peterson, Kristoffer
LU
; Wernersson, Sven
LU
; Brath, Ulrika
LU
; Leffler, Hakon
LU
and Oksanen, Esko
LU
, et al.
(2021)
In Journal of the American Chemical Society
1(4).
p.484-500
- Contribution to journal › Article
-
Mark
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression
Kim, Seok Jun ; Kang, Hyeok Gu ; Kim, Kyungeun ; Kim, Hoyoung ; Zetterberg, Fredrik ; Park, Young Soo ; Cho, Hyun Soo ; Hewitt, Stephen M. ; Chung, Joon Yong and Nilsson, Ulf J. LU
, et al.
(2021)
In Gastric Cancer
24(5).
p.1050-1062
- Contribution to journal › Article