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2024
Mark Myocardin related transcription factor and galectin-3 drives lipid accumulation in human blood vessels
Arévalo-Martinez, Marycarmen ^LU ; Ede, Jacob ^LU ; van der Have, Oscar ^LU ; Ritsvall, Olivia ^LU ; Zetterberg, Fredrik R ; Nilsson, Ulf J ^LU ; Leffler, Hakon ^LU ; Holmberg, Johan ^LU and Albinsson, Sebastian ^LU (2024) In Vascular Pharmacology 156.
- Contribution to journal › Article
Mark Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer
Zetterberg, Fredrik R. ; Peterson, Kristoffer ; Nilsson, Ulf J. ^LU ; Andréasson Dahlgren, Kajsa ; Diehl, Carl ; Hoyler, Ian ; Håkansson, Maria ; Khabut, Areej ^LU ; Kahl-Knutson, Barbro ^LU and Leffler, Hakon ^LU , et al. (2024) In Journal of Medicinal Chemistry
- Contribution to journal › Article
2023
Mark Discovery of Selective and Orally Available Galectin-1 Inhibitors
Zetterberg, Fredrik R ; Diehl, Carl ^LU ; Håkansson, Maria ^LU ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J ^LU ; Peterson, Kristoffer ^LU ; Roper, James A and Slack, Robert J (2023) In Journal of Medicinal Chemistry 66(24). p.16980-16990
- Contribution to journal › Article
Mark Resistance to anti-PD-1/anti-PD-L1 : galectin-3 inhibition with GB1211 reverses galectin-3-induced blockade of pembrolizumab and atezolizumab binding to PD-1/PD-L1
Mabbitt, Joseph ; Holyer, Ian D ; Roper, James A ; Nilsson, Ulf J ^LU ; Zetterberg, Fredrik R ; Vuong, Lynda ; Mackinnon, Alison C ; Pedersen, Anders and Slack, Robert J (2023) In Frontiers in Immunology 14.
- Contribution to journal › Article
Mark N-BAR and F-BAR proteins - Endophilin-A3 and PSTPIP1 - control clathrin-independent endocytosis of L1CAM
Lemaigre, Camille ; Ceuppens, Apolline ; Valades-Cruz, Cesar Augusto ; Ledoux, Benjamin ; Vanbeneden, Bastien ; Hassan, Mujtaba ^LU ; Zetterberg, Fredrik R. ; Nilsson, Ulf J ^LU ; Johannes, Ludger and Wunder, Christian , et al. (2023) In Traffic: the International Journal of Intracellular Transport 24(4). p.190-212
- Contribution to journal › Article
Mark Evaluating the affinity and kinetics of small molecule glycomimetics for human and mouse galectin-3 using surface plasmon resonance
Kim, Henry ; Weidner, Nathalie ; Ronin, Céline ; Klein, Emmanuel ; Roper, James A. ; Kahl-Knutson, Barbro ^LU ; Peterson, Kristoffer ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU and Pedersen, Anders , et al. (2023) In SLAS Discovery 28(5). p.233-239
- Contribution to journal › Article
2022
Mark Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease
Zetterberg, Fredrik R. ; Mackinnon, Alison ; Brimert, Thomas ; Gravelle, Lise ; Johnsson, Richard E. ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU ; Pedersen, Anders and Peterson, Kristoffer ^LU , et al. (2022) In Journal of Medicinal Chemistry 65(19). p.12626-12638
- Contribution to journal › Article
2020
Mark In Vivo Veritas : ¹⁸F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors
Bratteby, Klas ; Torkelsson, Edvard ; L'Estrade, Elina Tampio ; Peterson, Kristoffer ^LU ; Shalgunov, Vladimir ; Xiong, Mengfei ; Leffler, Hakon ^LU ; Zetterberg, Fredrik R. ; Olsson, Tomas G. ^LU and Gillings, Nic , et al. (2020) In Journal of Medicinal Chemistry 63(2). p.747-755
- Contribution to journal › Article
2019
Mark Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors
Dahlqvist, Alexander ^LU ; Zetterberg, Fredrik R. ; Leffler, Hakon ^LU and Nilsson, Ulf J. ^LU (2019) In MedChemComm 10(6). p.913-925
- Contribution to journal › Article
Mark 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-Sites for High-Affinity and High-Selectivity Inhibition of Galectin-3
Dahlqvist, Alexander ^LU ; Mandal, Santanu ^LU ; Peterson, Kristoffer ^LU ; Håkansson, Maria ^LU ; Logan, Derek T. ^LU ; Zetterberg, Fredrik R. ; Leffler, Hakon ^LU and Nilsson, Ulf J. ^LU (2019) In Molecules 24(24).
- Contribution to journal › Article

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