Hakon Leffler

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2022
Mark Increased synovial galectin-3 induce inflammatory fibroblast activation and osteoclastogenesis in patients with rheumatoid arthritis
Nielsen, M. A. ; Køster, D. ; Greisen, S. ; Troldborg, A. ; Stengaard-Pedersen, K. ; Junker, P. ; Hørslev-Petersen, K. ; Hetland, M. L. ; Østergaard, M. and Hvid, M. , et al. (2022) In Scandinavian Journal of Rheumatology
- Contribution to journal › Article
Mark Engineering the Ligand Specificity of the Human Galectin-1 by Incorporation of Tryptophan Analogues
Tobola, Felix ; Lepšík, Martin ; Zia, Syeda Rehana ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU ; Blixt, Ola ; Imberty, Anne and Wiltschi, Birgit (2022) In ChemBioChem
- Contribution to journal › Article
Mark Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins
Sun, Lingbo ; Konstantinidi, Andriana ; Ye, Zilu ; Nason, Rebecca ; Zhang, Yuecheng ; Büll, Christian ; Kahl-Knutson, Barbro ^LU ; Hansen, Lars ; Leffler, Hakon ^LU and Vakhrushev, Sergey Y. , et al. (2022) In Journal of Biological Chemistry 298(2).
- Contribution to journal › Article
2021
Mark Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside
Girardi, Benedetta ; Manna, Martina ; Van Klaveren, Sjors ^LU ; Tomašič, Tihomir ; Jakopin, Žiga ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU ; Ricklin, Daniel ; Mravljak, Janez and Schwardt, Oliver , et al. (2021) In ChemMedChem
- Contribution to journal › Article
Mark Synthesis and Biological Studies of O3-Aryl Galactosides as Galectin Inhibitors
Kervefors, Gabriella ; Pal, Kumar Bhaskar ; Tolnai, Gergely L. ; Mahanti, Mukul ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU and Olofsson, Berit (2021) In Helvetica Chimica Acta 104(2).
- Contribution to journal › Article
Mark Benzimidazole–galactosides bind selectively to the Galectin-8 N-Terminal domain : Structure-based design and optimisation
Hassan, Mujtaba ^LU ; van Klaveren, Sjors ^LU ; Håkansson, Maria ^LU ; Diehl, Carl ^LU ; Kovačič, Rebeka ; Baussière, Floriane ; Sundin, Anders P. ^LU ; Dernovšek, Jaka ; Walse, Björn ^LU and Zetterberg, Fredrik , et al. (2021) In European Journal of Medicinal Chemistry 223.
- Contribution to journal › Article
Mark Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression
Kim, Seok Jun ; Kang, Hyeok Gu ; Kim, Kyungeun ; Kim, Hoyoung ; Zetterberg, Fredrik ; Park, Young Soo ; Cho, Hyun Soo ; Hewitt, Stephen M. ; Chung, Joon Yong and Nilsson, Ulf J. ^LU , et al. (2021) In Gastric Cancer 24(5). p.1050-1062
- Contribution to journal › Article
Mark Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C
Wallerstein, Johan ^LU ; Ekberg, Vilhelm ^LU ; Misini Ignjatović, Majda ^LU ; Kumar, Rohit ^LU ; Caldararu, Octav ^LU ; Peterson, Kristoffer ^LU ; Wernersson, Sven ^LU ; Brath, Ulrika ^LU ; Leffler, Hakon ^LU and Oksanen, Esko ^LU , et al. (2021) In JACS Au 1(4). p.484-500
- Contribution to journal › Article
Mark Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
Hirani, Nikhil ; MacKinnon, Alison C. ; Nicol, Lisa ; Ford, Paul ; Schambye, Hans ; Pedersen, Anders ; Nilsson, Ulf J. ^LU ; Leffler, Hakon ^LU ; Sethi, Tariq and Tantawi, Susan , et al. (2021) In European Respiratory Journal 57(5).
- Contribution to journal › Article
Mark Structure-Guided Design of d -Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain
Hassan, Mujtaba ^LU ; Baussière, Floriane ; Guzelj, Samo ; Sundin, Anders P. ^LU ; Håkansson, Maria ; Kovačič, Rebeka ; Leffler, Hakon ^LU ; Tomašič, Tihomir ; Anderluh, Marko ^LU and Jakopin, Žiga , et al. (2021) In ACS Medicinal Chemistry Letters 12(11). p.1745-1752
- Contribution to journal › Article

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