Barbro Kahl Knutson

Division of Microbiology, Immunology and Glycobiology - MIG

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2023
Mark Evaluating the affinity and kinetics of small molecule glycomimetics for human and mouse galectin-3 using surface plasmon resonance
Kim, Henry ; Weidner, Nathalie ; Ronin, Céline ; Klein, Emmanuel ; Roper, James A. ; Kahl-Knutson, Barbro ^LU ; Peterson, Kristoffer ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU and Pedersen, Anders , et al. (2023) In SLAS Discovery 28(5). p.233-239
- Contribution to journal › Article
2022
Mark Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins
Sun, Lingbo ; Konstantinidi, Andriana ; Ye, Zilu ; Nason, Rebecca ; Zhang, Yuecheng ; Büll, Christian ; Kahl-Knutson, Barbro ^LU ; Hansen, Lars ; Leffler, Hakon ^LU and Vakhrushev, Sergey Y. , et al. (2022) In Journal of Biological Chemistry 298(2).
- Contribution to journal › Article
Mark Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease
Zetterberg, Fredrik R. ; Mackinnon, Alison ; Brimert, Thomas ; Gravelle, Lise ; Johnsson, Richard E. ; Kahl-Knutson, Barbro ^LU ; Leffler, Hakon ^LU ; Nilsson, Ulf J. ^LU ; Pedersen, Anders and Peterson, Kristoffer ^LU , et al. (2022) In Journal of Medicinal Chemistry 65(19). p.12626-12638
- Contribution to journal › Article
2019
Mark Extracellular and intracellular small-molecule galectin-3 inhibitors
Stegmayr, John ^LU ; Zetterberg, Fredrik ; Carlsson, Michael C. ^LU ; Huang, Xiaoli ^LU ; Sharma, Gunjan ^LU ; Kahl-Knutson, Barbro ^LU ; Schambye, Hans ; Nilsson, Ulf J. ^LU ; Oredsson, Stina ^LU and Leffler, Hakon ^LU (2019) In Scientific Reports 9(1).
- Contribution to journal › Article
2018
Mark Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands
Peterson, Kristoffer ^LU ; Collins, Patrick M. ; Huang, Xiaoli ^LU ; Kahl-Knutsson, Barbro ^LU ; Essén, Sofia ^LU ; Zetterberg, Fredrik R. ; Oredsson, Stina ^LU ; Leffler, Hakon ^LU ; Blanchard, Helen and Nilsson, Ulf J. ^LU (2018) In RSC Advances 8(44). p.24913-24922
- Contribution to journal › Article
Mark Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity
Peterson, Kristoffer ^LU ; Kumar, Rohit ^LU ; Stenström, Olof ^LU ; Verma, Priya ; Verma, Prashant R. ^LU ; Håkansson, Maria ; Kahl-Knutsson, Barbro ^LU ; Zetterberg, Fredrik ; Leffler, Hakon ^LU and Akke, Mikael ^LU , et al. (2018) In Journal of Medicinal Chemistry 61(3). p.1164-1175
- Contribution to journal › Article
2016
Mark Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition
Delaine, Tamara ^LU ; Collins, Patrick ; Mackinnon, Alison ; Sharma, G. ^LU ; Stegmayr, John ^LU ; Rajput, Vishal K. ; Mandal, Santanu ^LU ; Cumpstey, Ian ^LU ; Larumbe, Amaia and Salameh, Bader A. ^LU , et al. (2016) In ChemBioChem 17(18). p.1759-1770
- Contribution to journal › Article
Mark Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans
Stegmayr, John ^LU ; Lepur, Adriana ^LU ; Kahl Knutson, Barbro ^LU ; Aguilar-Moncayo, Matilde ; Klyosov, Anatole A. ; Field, Robert A. ; Oredsson, Stina ^LU ; Nilsson, Ulf ^LU and Leffler, Hakon ^LU (2016) In Journal of Biological Chemistry 291(25). p.13318-13334
- Contribution to journal › Article
2010
Mark Mutational tuning of galectin-3 specificity and biological function.
Salomonsson, Emma ^LU ; Carlsson, Michael ^LU ; Osla, Veronica ; Hendus-Altenburger, Ruth ; Kahl Knutson, Barbro ^LU ; Öberg, Christopher ^LU ; Sundin, Anders ^LU ; Nilsson, Rickard ; Nordberg Karlsson, Eva ^LU and Nilsson, Ulf ^LU , et al. (2010) In Journal of Biological Chemistry 285(45). p.35079-35091
- Contribution to journal › Article
2003
Mark Truncated galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer
John, CM ; Leffler, Hakon ^LU ; Kahl Knutson, Barbro ^LU ; Svensson, Inga ^LU and Jarvis, GA (2003) In Clinical Cancer Research 9(6). p.2374-2383
- Contribution to journal › Article

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