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- 2020
-
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
Hoban, Deirdre B LU ; Shrigley, Shelby LU
;
Mattsson, Bengt
LU
;
Breger, Ludivine S
LU
;
Jarl, Ulla
LU
;
Cardoso, Tiago
LU
;
Nelander Wahlestedt, Jenny
LU
;
Luk, Kelvin C
;
Björklund, Anders
LU
and
Parmar, Malin
LU
(2020)
In Proceedings of the National Academy of Sciences of the United States of America
Mark
- 2019
-
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
Adler, Andrew F. LU ; Cardoso, Tiago LU ; Nolbrant, Sara LU ; Mattsson, Bengt LU ; Hoban, Deirdre B. LU ; Jarl, Ulla LU ; Wahlestedt, Jenny Nelander LU ; Grealish, Shane LU ; Björklund, Anders LU
and
Parmar, Malin
LU
(2019)
In Cell Reports
28(13).
p.5-3473
Mark
- 2018
-
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, Tiago LU ; Adler, Andrew F. LU ; Mattsson, Bengt LU ; Hoban, Deirdre B. LU ; Nolbrant, Sara LU ; Wahlestedt, Jenny Nelander LU ; Kirkeby, Agnete LU ; Grealish, Shane LU ; Björklund, Anders LU
and
Parmar, Malin
LU
(2018)
In Journal of Comparative Neurology
526(13).
p.2133-2146
Mark
- 2017
-
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
Thakur, Poonam LU ; Breger, Ludivine S. LU ; Lundblad, Martin LU ; Wan, Oi Wan LU ; Mattsson, Bengt LU ; Luk, Kelvin C. ; Lee, Virginia Man Yee ; Trojanowski, John Q and Björklund, Anders LU
(2017)
In Proceedings of the National Academy of Sciences of the United States of America
114(39).
p.8284-8293
Mark
- 2016
-
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
LI, WEN LU ; Englund, Elisabet LU
;
Widner, Håkan
LU
;
Mattsson, Bengt
LU
;
van Westen, Danielle
LU
;
Lätt, Jimmy
LU
;
Rehncrona, Stig
LU
;
Brundin, Patrik
;
Björklund, Anders
LU
and
Lindvall, Olle
LU
, et al.
(2016)
In Proceedings of the National Academy of Sciences of the United States of America
113(23).
p.6544-6549
Mark
-
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
Wan, Oi Wan LU ; Shin, Eunju LU ; Mattsson, Bengt LU ; Caudal, Dorian ; Svenningsson, Per and Björklund, Anders LU
(2016)
In Scientific Reports
6.
Mark
- 2015
-
Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.
Volakakis, Nikolaos ; Tiklova, Katarina ; Decressac, Mickael LU ; Papathanou, Maria ; Mattsson, Bengt LU ; Gillberg, Linda ; Nobre, André ; Björklund, Anders LU
and
Perlmann, Thomas
(2015)
In Journal of Neuroscience
35(42).
p.14370-14385
Mark
- 2014
-
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.
Grealish, Shane LU ; Diguet, Elsa ; Kirkeby, Agnete LU ; Mattsson, Bengt LU ; Heuer, Andreas LU ; Bramoulle, Yann ; Van Camp, Nadja ; Perrier, Anselme L ; Hantraye, Philippe and Björklund, Anders LU
, et al.
(2014)
In Cell Stem Cell
15(5).
p.653-665
Mark
- 2013
-
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.
Decressac, Mickael LU ; Mattsson, Bengt LU ; Weikop, Pia ; Lundblad, Martin LU ; Jakobsson, Johan LU
and
Björklund, Anders
LU
(2013)
In Proceedings of the National Academy of Sciences
110(19).
p.1817-1826
Mark
- 2012
-
Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.
Decressac, Mickael LU ; Mattsson, Bengt LU ; Lundblad, Martin LU ; Weikop, P and Björklund, Anders LU
(2012)
In Neurobiology of Disease
45(3).
p.939-953
Mark