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- 2021
-
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease
Shrigley, Shelby LU
; Nilsson, Fredrik
LU
; Mattsson, Bengt
LU
; Fiorenzano, Alessandro
LU
; Mudannayake, Janitha
LU
; Bruzelius, Andreas
LU
; Ottosson, Daniella Rylander
LU
; Björklund, Anders
LU
; Hoban, Deirdre B
LU
and Parmar, Malin
LU
(2021)
In Journal of Parkinson's Disease
11(2).
p.515-528
Mark
- 2020
-
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD
Hoban, Deirdre B LU ; Shrigley, Shelby LU
; Mattsson, Bengt
LU
; Breger, Ludivine S
LU
; Jarl, Ulla
LU
; Cardoso, Tiago
LU
; Nelander Wahlestedt, Jenny
LU
; Luk, Kelvin C
; Björklund, Anders
LU
and Parmar, Malin
LU
(2020)
In Proceedings of the National Academy of Sciences of the United States of America
117(26).
p.15209-15220
Mark
- Light sheet fluorescence microscopy of optically cleared brains for studying the glymphatic system
- 2019
-
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease
Adler, Andrew F. LU ; Cardoso, Tiago LU ; Nolbrant, Sara LU ; Mattsson, Bengt LU ; Hoban, Deirdre B. LU ; Jarl, Ulla LU ; Wahlestedt, Jenny Nelander LU ; Grealish, Shane LU ; Björklund, Anders LU
and Parmar, Malin
LU
(2019)
In Cell Reports
28(13).
p.5-3473
Mark
- 2018
- Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum
-
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats
Cardoso, Tiago LU ; Adler, Andrew F. LU ; Mattsson, Bengt LU ; Hoban, Deirdre B. LU ; Nolbrant, Sara LU ; Wahlestedt, Jenny Nelander LU ; Kirkeby, Agnete LU ; Grealish, Shane LU ; Björklund, Anders LU
and Parmar, Malin
LU
(2018)
In Journal of Comparative Neurology
526(13).
p.2133-2146
Mark
- 2017
-
Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain
Thakur, Poonam LU ; Breger, Ludivine S. LU ; Lundblad, Martin LU ; Wan, Oi Wan LU ; Mattsson, Bengt LU ; Luk, Kelvin C. ; Lee, Virginia Man Yee ; Trojanowski, John Q and Björklund, Anders LU
(2017)
In Proceedings of the National Academy of Sciences of the United States of America
114(39).
p.8284-8293
Mark
- 2016
-
Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain.
LI, WEN LU ; Englund, Elisabet LU
; Widner, Håkan
LU
; Mattsson, Bengt
LU
; van Westen, Danielle
LU
; Lätt, Jimmy
LU
; Rehncrona, Stig
LU
; Brundin, Patrik
; Björklund, Anders
LU
and Lindvall, Olle
LU
, et al.
(2016)
In Proceedings of the National Academy of Sciences of the United States of America
113(23).
p.6544-6549
Mark
-
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
Wan, Oi Wan LU ; Shin, Eunju LU ; Mattsson, Bengt LU ; Caudal, Dorian ; Svenningsson, Per and Björklund, Anders LU
(2016)
In Scientific Reports
6.
Mark
-
DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
Aldrin-Kirk, Patrick LU ; Heuer, Andreas LU ; Wang, Gang LU ; Mattsson, Bengt LU ; Lundblad, Martin LU ; Parmar, Malin LU
and Björklund, Tomas
LU
(2016)
In Neuron
90(5).
p.955-968
Mark