Pekka Jaako (Former)
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- 2017
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Mark
Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia
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- Contribution to journal › Article
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Mark
Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
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- Contribution to journal › Article
- 2015
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Mark
Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.
(
- Contribution to journal › Article
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Mark
Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
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- Contribution to journal › Article
- 2014
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Mark
Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation.
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- Contribution to journal › Article
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Mark
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
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- Contribution to journal › Article
- 2012
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Mark
SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q- myelodysplastic syndrome.
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- Contribution to journal › Article
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Mark
Modeling Diamond-Blackfan Anemia in the Mouse: Disease Pathogenesis and Evaluation of Novel Therapies
(
- Thesis › Doctoral thesis (compilation)
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Mark
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
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- Contribution to journal › Article
- 2011
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Mark
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
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- Contribution to journal › Article
- 2010
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Mark
Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia
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- Contribution to journal › Published meeting abstract
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Mark
Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
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- Contribution to journal › Article
- 2009
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Mark
A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition
(
- Contribution to journal › Published meeting abstract