Shubhranshu Debnath (Former)

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2022
Mark Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector
Liu, Yang ^LU ; Dahl, Maria ^LU ; Debnath, Shubhranshu ^LU ; Rothe, Michael ; Smith, Emma ^LU ; Tan Grahn, Hooi Min ^LU ; Warsi, Sarah ^LU ; Chen, Jun ^LU ; Flygare, Johan ^LU and Schambach, Axel , et al. (2022) In Haematologica 107(2). p.446-456
- Contribution to journal › Article
2021
Mark Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype
Dahl, Maria ^LU ; Warsi, Sarah ^LU ; Liu, Yang ^LU ; Debnath, Shubhranshu ^LU ; Billing, Matilda ^LU ; Siva, Kavitha ^LU ; Flygare, Johan ^LU and Karlsson, Stefan ^LU (2021) In Experimental Hematology 99. p.2-53
- Contribution to journal › Article
2020
Mark Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171
Subramaniam, Agatheeswaran ^LU ; Zemaitis, Kristijonas ^LU ; Safaee Talkhoncheh, Mehrnaz ^LU ; Yudovich, David ^LU ; Bäckström, Alexandra ^LU ; Debnath, Shubhranshu ^LU ; Chen, Jun ^LU ; Jain, Mayur Vilas ^LU ; Galeev, Roman ^LU and Gaetani, Massimiliano , et al. (2020) In Blood 136(19). p.2151-2161
- Contribution to journal › Article
2018
Mark Small Molecule Screens Identify CDK8-Inhibitors As Candidate Diamond-Blackfan Anemia Drugs
Chen, Jun ^LU ; Siva, Kavitha ^LU ; Rzymski, Tomasz ; Johansson, Lars ; Lundbäck, Thomas ; Nunez villacis, Lorena ; Ek, Fredrik ^LU ; Wang, Bingrui ; George, Amee J and Wan, Yang , et al. (2018) In Blood 132(Supplement 1). p.753-753
- Contribution to journal › Published meeting abstract
2017
Mark Development of novel therapies for Diamond-Blackfan Anemia
Debnath, Shubhranshu ^LU (2017)
- Thesis › Doctoral thesis (compilation)
Mark Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
Debnath, Shubhranshu ^LU ; Jaako, Pekka ^LU ; Siva, Kavitha ^LU ; Rothe, Michael ; Chen, Jun ^LU ; Dahl, Maria ^LU ; Gaspar, H. Bobby ; Flygare, Johan ^LU ; Schambach, Axel and Karlsson, Stefan ^LU (2017) In Molecular Therapy 25(8). p.1805-1814
- Contribution to journal › Article
Mark Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
Komorowska, Karolina ^LU ; Doyle, Alexander ^LU ; Wahlestedt, Martin ^LU ; Subramaniam, Agatheeswaran ^LU ; Debnath, Shubhranshu ^LU ; Chen, Jun ^LU ; Soneji, Shamit ^LU ; Van Handel, Ben ; Mikkola, Hanna K.A. and Miharada, Kenichi ^LU , et al. (2017) In Cell Reports 21(12). p.3514-3523
- Contribution to journal › Article
2015
Mark Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
Jaako, Pekka ^LU ; Debnath, Shubhranshu ^LU ; Olsson, Karin ^LU ; Zhang, Y ; Flygare, Johan ^LU ; Lindström, M S ; Bryder, David ^LU and Karlsson, Stefan ^LU (2015) In Leukemia 29(11). p.2221-2229
- Contribution to journal › Article
2014
Mark Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
Jaako, Pekka ^LU ; Debnath, Shubhranshu ^LU ; Olsson, Karin ^LU ; Modlich, Ute ; Rothe, Michael ; Schambach, Axel ; Flygare, Johan ^LU and Karlsson, Stefan ^LU (2014) In Haematologica 99(12). p.1792-1798
- Contribution to journal › Article
2012
Mark Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
Jaako, Pekka ^LU ; Debnath, Shubhranshu ^LU ; Olsson, Karin ^LU ; Bryder, David ^LU ; Flygare, Johan ^LU and Karlsson, Stefan ^LU (2012) In Blood 120(11). p.2225-2228
- Contribution to journal › Article