Shubhranshu Debnath
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- 2020
- Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171
- 2017
- Development of novel therapies for Diamond-Blackfan Anemia
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Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia
Debnath, Shubhranshu LU ; Jaako, Pekka LU ; Siva, Kavitha LU ; Rothe, Michael ; Chen, Jun LU ; Dahl, Maria LU ; Gaspar, H. Bobby ; Flygare, Johan LU ; Schambach, Axel and Karlsson, Stefan LU
(2017)
In Molecular Therapy
25(8).
p.1805-1814
Mark
- Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration
- 2015
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Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.
Jaako, Pekka LU ; Debnath, Shubhranshu LU ; Olsson, Karin LU ; Zhang, Y ; Flygare, Johan LU ; Lindström, M S ; Bryder, David LU and Karlsson, Stefan LU
(2015)
In Leukemia
29(11).
p.2221-2229
Mark
- 2014
-
Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.
Jaako, Pekka LU ; Debnath, Shubhranshu LU ; Olsson, Karin LU ; Modlich, Ute ; Rothe, Michael ; Schambach, Axel ; Flygare, Johan LU and Karlsson, Stefan LU
(2014)
In Haematologica
99(12).
p.1792-1798
Mark
- 2012
-
Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
Jaako, Pekka LU ; Debnath, Shubhranshu LU ; Olsson, Karin LU ; Bryder, David LU ; Flygare, Johan LU and Karlsson, Stefan LU
(2012)
In Blood
120(11).
p.2225-2228
Mark