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- 2022
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A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY
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- Contribution to journal › Article
- 2020
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Low-cost exercise interventions improve long-term cardiometabolic health independently of a family history of type 2 diabetes : a randomized parallel group trial
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- Contribution to journal › Article
- 2019
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The associations of daylight and melatonin receptor 1B gene rs10830963 variant with glycemic traits : the prospective PPP-Botnia study
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- Contribution to journal › Article
- 2018
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Melatonin receptor 1B gene rs10830963 polymorphism, depressive symptoms and glycaemic traits
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- Contribution to journal › Article
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HAPT2D : high accuracy of prediction of T2D with a model combining basic and advanced data depending on availability
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- Contribution to journal › Article
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Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin
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- Contribution to journal › Article
- 2016
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Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes
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- Contribution to journal › Article
- 2015
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Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts
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- Contribution to journal › Article
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Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus.
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- Contribution to journal › Article
- 2014
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Sleep duration and insulin resistance in individuals without type 2 diabetes: The PPP-Botnia Study
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- Contribution to journal › Article
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Genome Wide Meta-analysis Highlights the Role of Genetic Variation in RARRES2 in the Regulation of Circulating Serum Chemerin.
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- Contribution to journal › Article
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A Central Role for GRB10 in Regulation of Islet Function in Man.
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- Contribution to journal › Article
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Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
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- Contribution to journal › Article
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Mark
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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- Contribution to journal › Article
- 2013
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The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
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- Contribution to journal › Article
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Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
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- Contribution to journal › Article
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A link between GIP and osteopontin in adipose tissue and insulin resistance.
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- Contribution to journal › Article
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The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
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- Contribution to journal › Article
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Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
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- Contribution to journal › Article
- 2012
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Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study
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- Contribution to journal › Article
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Mark
Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: Results from the PPP-Botnia Study
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- Contribution to journal › Article
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Subjective Sleep Complaints Are Associated With Insulin Resistance in Individuals Without Diabetes The PPP-Botnia Study
(
- Contribution to journal › Article
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Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time
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- Contribution to journal › Article
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No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
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- Contribution to journal › Article
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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- Contribution to journal › Article
- 2011
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Mark
Facilitation of information exhange between genetic research, primary health care and decision makers using a regional diabetes register DIREVA (Diabetes Register Vaasa)
2011) 5th International Multi-Conference on Society, Cybernetics and Informatics, IMSCI 2011 1. p.288-288(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
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Mark
A common variant near the PRL gene is associated with increased adiposity in males
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- Contribution to journal › Article
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Mark
Depressive Symptoms, Antidepressant Medication Use, and Insulin Resistance The PPP-Botnia Study
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- Contribution to journal › Article
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Mark
Two common genetic variants near nuclear encoded OXPHOS genes are associated with insulin secretion in vivo.
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- Contribution to journal › Article
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Mark
Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies
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- Contribution to journal › Article
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Mark
Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants
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- Contribution to journal › Article
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Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
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- Contribution to journal › Article
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Mark
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
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- Contribution to journal › Article
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Mark
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
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- Contribution to journal › Article
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Mark
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
(
- Contribution to journal › Article
- 2010
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Mark
Stressful Life Events and the Metabolic Syndrome - The Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia Study
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- Contribution to journal › Article
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Mark
GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population
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- Contribution to journal › Article
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Mark
Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years
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- Contribution to journal › Article
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Mark
Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans
(
- Chapter in Book/Report/Conference proceeding › Paper in conference proceeding
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Mark
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
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- Contribution to journal › Article
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Mark
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
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- Contribution to journal › Article
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Mark
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
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- Contribution to journal › Article
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Mark
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
(
- Contribution to journal › Article
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Mark
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
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- Contribution to journal › Article
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Mark
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
(
- Contribution to journal › Article
- 2009
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Mark
Genetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twins.
(
- Contribution to journal › Article
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Mark
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
(
- Contribution to journal › Article
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Mark
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts
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- Contribution to journal › Article
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Mark
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.
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- Contribution to journal › Article
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Mark
Variants in MTNR1B influence fasting glucose levels
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- Contribution to journal › Article
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Mark
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
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- Contribution to journal › Article
- 2008
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Mark
Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes
(
- Contribution to journal › Article
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Mark
Clinical risk factors, DNA variants, and the development of type 2 diabetes.
(
- Contribution to journal › Article
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Mark
Identification of ten loci associated with height highlights new biological pathways in human growth
(
- Contribution to journal › Article
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Mark
Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
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- Contribution to journal › Article
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Mark
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
(
- Contribution to journal › Article
- 2007
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Mark
Variation in GYS1 Interacts with Exercise and Gender to Predict Cardiovascular Mortality.
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- Contribution to journal › Article
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Mark
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts
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- Contribution to journal › Article
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Mark
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
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- Contribution to journal › Article
- 2006
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Mark
Complex Relationship Between Blood Pressure and Mortality in Type 2 Diabetic Patients. A Follow-Up of the Botnia Study.
(
- Contribution to journal › Article
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Mark
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
(
- Contribution to journal › Article
- 2005
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Mark
Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.
(
- Contribution to journal › Article