Kinetic Modelling of Fluidised Bed Drying of Enzyme Granules and Effect on Enzyme Stability
(2019) KBTM05 20191Biotechnology (MSc)
- Abstract
- In the production of solid enzyme products, the granules are dried in a fluidised bed dryer prior to being coated with a protective salt coating. The coating exhibits a low mass diffusivity, which essentially encapsulates any present moisture inside. During the coating process moisture is inevitably added to the granules. It has prior been shown that moisture content in the final product has a negative impact on the shelflife stability of some of the enzyme product produced by Novozymes. It has been theorised whether it is the moisture of the granules before the coating is applied, or the moisture added during the coating which accounts for this effect.
The primary objective in this thesis was to determine the correlation between... (More) - In the production of solid enzyme products, the granules are dried in a fluidised bed dryer prior to being coated with a protective salt coating. The coating exhibits a low mass diffusivity, which essentially encapsulates any present moisture inside. During the coating process moisture is inevitably added to the granules. It has prior been shown that moisture content in the final product has a negative impact on the shelflife stability of some of the enzyme product produced by Novozymes. It has been theorised whether it is the moisture of the granules before the coating is applied, or the moisture added during the coating which accounts for this effect.
The primary objective in this thesis was to determine the correlation between moisture content from the dryer and the final products shelf-life stability. From experimental data a clear correlation was observed. A considerably decrease in absolute enzyme activity was observed when the coating was performed with high moisture content granules. It is thought that high moisture content combined with a high temperature cause the enzymes to denature. Furthermore a mathematical model was implemented in Python to simulate the drying. The simulations were shown to predict the moisture content of the granules well to the experimental data. However the simulated temperatures deviates considerably from measured values. (Less) - Popular Abstract
- In most laundry detergents today enzymes are used to improve the removal of those hard to remove stains. Further, the use of enzymes allow for washing at lower temperatures and still remove stains, making enzymes an important contribution in reducing energy consumption. Although enzymes has an expiration date. The Danish biotechnology company Novozymes A/S is a world leading producer of, inter alia, enzymes which are used in detergent, and they are interested in if the expiration date of the enzymes can be extended.
Please use this url to cite or link to this publication:
http://lup.lub.lu.se/student-papers/record/8998201
- author
- Ingmarsson, Edvin LU
- supervisor
-
- Carl Grey LU
- Pär Tufvesson LU
- organization
- course
- KBTM05 20191
- year
- 2019
- type
- H2 - Master's Degree (Two Years)
- subject
- keywords
- fluidised bed, drying, enzyme, stability, mathematical modelling, biotechnology, bioteknik
- language
- English
- id
- 8998201
- date added to LUP
- 2019-12-20 10:44:28
- date last changed
- 2019-12-20 10:44:28
@misc{8998201,
abstract = {{In the production of solid enzyme products, the granules are dried in a fluidised bed dryer prior to being coated with a protective salt coating. The coating exhibits a low mass diffusivity, which essentially encapsulates any present moisture inside. During the coating process moisture is inevitably added to the granules. It has prior been shown that moisture content in the final product has a negative impact on the shelflife stability of some of the enzyme product produced by Novozymes. It has been theorised whether it is the moisture of the granules before the coating is applied, or the moisture added during the coating which accounts for this effect.
The primary objective in this thesis was to determine the correlation between moisture content from the dryer and the final products shelf-life stability. From experimental data a clear correlation was observed. A considerably decrease in absolute enzyme activity was observed when the coating was performed with high moisture content granules. It is thought that high moisture content combined with a high temperature cause the enzymes to denature. Furthermore a mathematical model was implemented in Python to simulate the drying. The simulations were shown to predict the moisture content of the granules well to the experimental data. However the simulated temperatures deviates considerably from measured values.}},
author = {{Ingmarsson, Edvin}},
language = {{eng}},
note = {{Student Paper}},
title = {{Kinetic Modelling of Fluidised Bed Drying of Enzyme Granules and Effect on Enzyme Stability}},
year = {{2019}},
}