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Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.

Herlin, Maria LU ; McGuigan, Fiona LU orcid ; Luthman, Holger LU and Åkesson, Kristina LU (2015) In Bone 79. p.105-109
Abstract
ALOX12 and ALOX15 encode arachidonate lipoxygenases which produce lipid metabolites involved in inflammatory processes. Metabolites generated by ALOX12 and ALOX15 can activate the expression of the potent pro-inflammatory cytokine IL-6, and produce endogenous ligands for PPARG. In this study, polymorphisms in ALOX12, ALOX15, IL6 and PPARG were investigated for association with bone properties in young and elderly Swedish women.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bone
volume
79
pages
105 - 109
publisher
Elsevier
external identifiers
  • pmid:26036173
  • wos:000359509700015
  • scopus:84930945200
  • pmid:26036173
ISSN
1873-2763
DOI
10.1016/j.bone.2015.05.035
language
English
LU publication?
yes
id
76e52e2e-a51e-4757-a31f-d256ddf66e3e (old id 7508486)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26036173?dopt=Abstract
date added to LUP
2016-04-01 10:26:49
date last changed
2023-08-31 03:04:06
@article{76e52e2e-a51e-4757-a31f-d256ddf66e3e,
  abstract     = {{ALOX12 and ALOX15 encode arachidonate lipoxygenases which produce lipid metabolites involved in inflammatory processes. Metabolites generated by ALOX12 and ALOX15 can activate the expression of the potent pro-inflammatory cytokine IL-6, and produce endogenous ligands for PPARG. In this study, polymorphisms in ALOX12, ALOX15, IL6 and PPARG were investigated for association with bone properties in young and elderly Swedish women.}},
  author       = {{Herlin, Maria and McGuigan, Fiona and Luthman, Holger and Åkesson, Kristina}},
  issn         = {{1873-2763}},
  language     = {{eng}},
  pages        = {{105--109}},
  publisher    = {{Elsevier}},
  series       = {{Bone}},
  title        = {{Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly.}},
  url          = {{https://lup.lub.lu.se/search/files/1852421/8565860.pdf}},
  doi          = {{10.1016/j.bone.2015.05.035}},
  volume       = {{79}},
  year         = {{2015}},
}